Alzheimer's disease & dementia

Effects of amyloid beta plaque on different brain cells

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies. This is the conclusion of a study led by researchers at Linköping University in Sweden. ...

Neuroscience

An immunological memory in the brain

Inflammatory reactions can change the brain's immune cells in the long term—meaning that these cells have an "immunological memory." This memory may influence the progression of neurological disorders that occur later in ...

Alzheimer's disease & dementia

Improving brain function in Alzheimer's disease mouse model

Using two complementary approaches to reduce the deposits of amyloid-beta in the brain rather than either approach alone improved spatial navigation and memory in a mouse model of Alzheimer's disease. These findings suggest ...

Alzheimer's disease & dementia

Sleepless nights show ties to Alzheimer's risk

Even one night of lost sleep may cause the brain to fill with protein chunks that have long been linked to the development of Alzheimer's disease, a new study warns.

Alzheimer's disease & dementia

Antibody removes Alzheimer's plaques, in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a ...

Neuroscience

Does menopausal hormone therapy maintain the brain?

Taking menopausal hormone therapy soon after menopause to relieve symptoms may also benefit the brain, according to a study published in the March 21, 2018, online issue of Neurology, the medical journal of the American Academy ...

Medical research

Protein analysis for personalised medicine

New knowledge about proteins helps researchers develop innovative solutions for clinical practice, for example to the benefit of patients with Parkinsons's disease.

Alzheimer's disease & dementia

The brain's immune system may be key to new Alzheimer's treatments

Sanford Burnham Prebys Medical Research Institute (SBP) researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins ...

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