Alzheimer's disease & dementia
Alzheimer's damage in mice reduced with compound that targets APOE gene
People who carry the APOE4 genetic variant face a substantial risk for developing Alzheimer's disease.
Dec 6, 2017
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Page 4 - News tagged with beta-amyloid plaques
Neuroscience
Neuroscientists identify genetic changes in microglia in a mouse model of neurodegeneration and Alzheimer's disease
Microglia, immune cells that act as the central nervous system's damage sensors, have recently been implicated in Alzheimer's disease.
Oct 13, 2017
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Alzheimer's disease & dementia
Alzheimer's gene poses both risk and benefits
Scientists drilling down to the molecular roots of Alzheimer's disease have encountered a good news/bad news scenario. A major player is a gene called TREM2, mutations of which can substantially raise a person's risk of the ...
Oct 9, 2017
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Alzheimer's disease & dementia
Researchers help find pathologic hallmarks of Alzheimer's in aged chimpanzee brains
Dementia affects one-third of all people older than 65 years in the United States. The most common cause of dementia is Alzheimer's disease, a progressive, irreversible brain disease that results in impaired cognitive functioning ...
Aug 1, 2017
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Alzheimer's disease & dementia
BACE-Inhibitor successfully tested in Alzheimer's animal model
The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments. ...
Jul 28, 2017
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Alzheimer's disease & dementia
Blood test identifies key Alzheimer's marker
A new study led by researchers at Washington University School of Medicine in St. Louis suggests that measures of amyloid beta in the blood have the potential to help identify people with altered levels of amyloid in their ...
Jul 19, 2017
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Alzheimer's disease & dementia
Earlier Alzheimer's diagnosis may be possible with new imaging compound
By the time unambiguous signs of memory loss and cognitive decline appear in people with Alzheimer's disease, their brains already are significantly damaged, dotted with clumps of a destructive protein known as amyloid beta. ...
Nov 2, 2016
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Alzheimer's disease & dementia
Trial drug shows 'impressive' Alzheimer's action: study
An experimental drug cleared protein buildup in the brains of people with mild Alzheimer's disease and slowed their mental decline, the results of a preliminary trial showed Wednesday.
Aug 31, 2016
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Alzheimer's disease & dementia
Genetically engineered mice suggest new model for how Alzheimer's causes dementia
Using a novel, newly developed mouse model that mimics the development of Alzheimer's disease in humans, Johns Hopkins researchers say they have been able to determine that a one-two punch of major biological "insults" must ...
Jul 4, 2016
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Medical research
Human amyloid-beta acts as natural antibiotic in the brains of animal models
A new study from Massachusetts General Hospital (MGH) investigators provides additional evidence that amyloid-beta protein - which is deposited in the form of beta-amyloid plaques in the brains of patients with Alzheimer's ...
May 25, 2016
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