The present variants of cancer immunotherapy such as immune checkpoint blockades only benefit a small subset of patients due to its immunosuppressive tumor microenvironment. The capacity to vaccinate tumors and reduce immunosuppression ...
New insights into a population of tumor-infiltrating T cells may ultimately allow doctors to predict how patients will respond to checkpoint blockade immunotherapy, a form of cancer treatment with advantages that doctors ...
Researchers at the Washington University School of Medicine, St. Louis, have discovered a potential new target for cancer immunotherapy in transposable elements (TEs), short segments of DNA that can move around the genome.
A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg-Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new ...
Mar 1, 2021
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A second biological pathway that signals immune cells not to engulf and kill cancer cells has been identified by researchers at the Stanford University School of Medicine.
Nov 27, 2017
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Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of ...
Apr 2, 2015
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By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably to these treatments.
Aug 6, 2024
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Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering ...
Jul 16, 2024
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As we age, our immune systems start to flag, leaving us more susceptible to cancer and infections—and less responsive to vaccines and cancer immunotherapies.
Jul 12, 2024
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Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health ...
Jul 11, 2024
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