Oncology & Cancer

Restoring men's fertility after cancer

A tragic side-effect of chemotherapy might soon be a thing of the past, with researchers uncovering a vital pathway to restoring men's fertility after cancer.

Oncology & Cancer

Immune therapy targets cells that cause leukemia relapse

Genetically engineered immune cells successfully target the specific cancer cells that may be responsible for relapse of acute myeloid leukemia (AML), a type of blood cancer, and proved effective in animal models of the disease, ...

Medical research

Impact of DNA mutations on lifelong blood cell production uncovered

New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life. Scientists at the Wellcome Sanger Institute, the Cambridge Stem Cell Institute, EMBL's European Bioinformatics ...

Oncology & Cancer

Discovery could lead to better cancer immunotherapy

A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body's defenses against cancerous tumors. The discovery could lead to more effective cancer immunotherapy, ...

Oncology & Cancer

Patient-derived and mouse endo-ectocervical organoid generation

A few stem cells, various growth factors, four to six weeks of time—and, of course, a great deal of expertise—are needed to create a scaled-down but nevertheless lifelike and functional replica of a cervix in the laboratory.

Oncology & Cancer

New regulator of prostate cancer metastasis discovered

A transcription factor normally associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis, according to a Northwestern Medicine study published in Nature Genetics.

Medical research

Frozen testicular tissue still viable after two decades

Male testis tissue that is cryopreserved can be reimplanted after more than 20 years and will go on to make viable sperm, according to a new study in rodents in the open-access journal PLOS Biology by Eoin Whelan of the School ...

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