By means of experiments in mice, researchers have made discoveries about the mechanisms involved in dental pulp inflammation and root apex damage that pave the way for a search for medications that can be used to inhibit ...
Oct 5, 2023
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14
Memory B cells depend on autophagy for their survival, but the protein Rubicon is thought to hinder this process. Researchers from Osaka University have discovered a shorter isoform of Rubicon called RUBCN100, which enhances ...
Oct 2, 2023
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Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.
Jul 14, 2023
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N6-methyladenosine (m6A) is the most extensive studied RNA modification across various species, and the important effect of m6A modification in immune systems has been revealed in distinct contexts, including mRNA metabolism, ...
Jul 14, 2023
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The development of hepatocellular carcinoma, liver cancer, is known to involve the abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, until now.
Jun 28, 2023
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A stem cell therapy treatment developed by Duke-NUS Medical School researchers for heart failure has shown promising results in preclinical trials. These cells, when transplanted into an injured heart, are able to repair ...
Jun 8, 2023
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Immune cells play important roles in mediating allograft rejection and tolerance after cardiac transplantation. However, immune cell heterogeneity at the single-cell level, and how immune cell states shape transplantation ...
May 25, 2023
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Normally the lining of the colon forms a series of steep hills and valleys. At the surface, where the hills peak, are functional colon cells that do the organ's work of absorption and secretion. Deep in the valleys are stem ...
Mar 29, 2023
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136
Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation. Insights may help investigators ...
Mar 14, 2023
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Scientists at the Francis Crick Institute have uncovered how cells lining the lung airways change their metabolism, and how this process is key to helping the lungs heal after infection or damage.
Feb 13, 2023
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