Oncology & Cancer

Overstuffed cancer cells may have an Achilles' heel

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry ...

Oncology & Cancer

Addicted to ran, ovarian cancer cells stop moving when deprived

Did you know that 90% of cancer patients die from distant metastasis? The latter occurs when cancer cells have the ability to move within the patient's body and invade its healthy tissues. In a study published in Nature Communications, ...

Oncology & Cancer

Researchers identify new way to make cancer self-destruct

For years, researchers have been trying to target a gene called MYC that is known to drive tumor growth in multiple cancer types when it is mutated or over-expressed, but hitting that target successfully has proven difficult. ...

Medical research

A new strategy 'raises the volume' of gut-body communication

Throughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells and, although they comprise only a small population of the total cells, they are one of the most important moderators ...

Oncology & Cancer

Nutritional cues regulate pancreatic tumor's 'cell drinking'

Desperate for nutrients, rapidly growing pancreatic tumors resort to scavenging "fuel" through an alternative supply route, called macropinocytosis. Scientists are hopeful that blocking this process, often described as "cellular ...

Medical research

Treatment for common cause of diarrhea more promising

One of the most common causes of diarrhea worldwide—accounting for millions of cases and tens of thousands of deaths, mostly of small children—is the parasite Cryptosporidium. Doctors can treat children with Cryptosporidium ...

Oncology & Cancer

Drug-resistant cancer cells create own Achilles heel

The cells of most patients' cancers are resistant to a class of drugs, called proteasome inhibitors, that should kill them. When studied in the lab, these drugs are highly effective, yet hundreds of clinical trials testing ...

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