Diseases, Conditions, Syndromes

New insights into the cellular response to SARS-CoV-2 infection

The COVID-19 pandemic caused by the new coronavirus has created an unprecedented public health challenge globally. Little was known about how the infecting cells respond to the virus and how the virus hijacks the host cellular ...

Medical research

New construction role found for cell demolition tool

A new role has been discovered for a well-known piece of cellular machinery, which could revolutionise the way we understand how tissue is constructed and remodelled within the body.

Oncology & Cancer

Clinical trials for cancer, one patient at a time

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time. The patient's tumor is "reverse engineered" ...

Genetics

In cancer, an embryonic gene-silencing mechanism gone awry

There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our ...

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