While previous studies have investigated the function of the protein Bcl6 in dendritic cells—in some cases with varying results—a new study published in Nature Communications has sought to harmonize the sometimes contradictory ...
Apr 30, 2024
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Traditionally, therapies combining DNA-damaging agents and STING agonists have shown potential in treating cancer by enhancing immune response and reshaping the tumor microenvironment. However, until now, creating a single ...
Mar 20, 2024
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Patients with lupus nephritis (LN), a severe complication of systemic lupus erythematosus (SLE), often undergo progressive kidney damage, with approximately 20% of these patients advancing to end-stage renal disease.
Dec 13, 2023
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Researchers from the Jan Dobeš laboratory at Charles University in Prague have made a significant discovery uncovering a novel immune response in the intestinal epithelium. Furthermore, their study delineates a mechanism ...
Oct 31, 2023
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Dendritic cells play a key role in the mammalian immune system. These cells are present throughout the human body and are known to capture foreign bodies, or antigens, using extendable "arms" called dendrites. Once captured, ...
Oct 30, 2023
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Vaccines work by giving our immune system a 'heads up' about a known threat. They are traditionally given before we encounter a pathogen (such as the influenza virus), allowing our bodies to mount a better immune response ...
Oct 18, 2023
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A dendritic cell vaccine administered before and after autologous stem cell transplant (ASCT) was safe and immunogenic and was associated with durable clinical responses in patients with high-risk multiple myeloma, according ...
Sep 22, 2023
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A team led by Prof. Tian Zhigang and Prof. Peng Hui from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS), in collaboration with Prof. Zhang Zemin from Peking University, have ...
Sep 12, 2023
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A new research paper was published on the cover of Aging, titled "Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging."
Aug 31, 2023
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A recent study revealed that a protein important for neuron communication is associated with patient resistance to Alzheimer's disease and may delay cognitive decline.
Apr 27, 2023
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