Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting ...
Jan 3, 2013
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Depriving cancer cells of a key amino acid dramatically cuts their ability to grow and multiply, according to a new Cancer Research UK study published in Nature.
Dec 18, 2012
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Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant ...
Dec 9, 2012
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A new study about Human Cytomegalovirus (HCMV), a leading cause of birth defects, reveals how the virus co-opts cells' abilities to repair themselves. In the paper published on November 29 in the Open Access journal PLOS ...
Nov 29, 2012
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New understanding of how drugs called PARP inhibitors, which have already shown promise for the treatment of women with familial breast and ovarian cancers linked to BRCA mutations, exert their anticancer effects has led ...
Nov 9, 2012
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A person doesn't have to go far to find a polycyclic aromatic hydrocarbon (PAH). These carcinogen precursors are inhaled through automobiles exhaust during the morning commute, are present in a drag of cigarette smoke, and ...
Nov 2, 2012
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(Medical Xpress)—In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors.
Nov 1, 2012
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In a comparison of strategies to identify individuals with Lynch syndrome, the most common form of hereditary colorectal cancer (CRC), caused by mutations in certain genes (DNA mismatch repair [MMR] genes), universal tumor ...
Oct 16, 2012
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Milk consumption has been linked to improved health, with decreased risks of diabetes, metabolic syndrome, and colon cancer. A group of scientists in Sweden found that lactoferricin4-14 (Lfcin4-14), a milk protein with known ...
Oct 3, 2012
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Radiation therapy is one of the most widely used cancer treatments, but it often damages normal tissue and can lead to debilitating conditions. A class of drugs known as mammalian target of rapamycin (mTOR) inhibitors can ...
Sep 6, 2012
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