Researchers from the Butantan Institute and collaborators are developing a more potent version of the BCG vaccine that protects against tuberculosis. While the conventional immunizer reduced infection by 90% in experiments ...
Jul 3, 2024
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The cerebellum is a region of the brain that helps us refine our movements and learn new motor skills. Patients and mouse models experience many kinds of abnormal movements when their cerebellum is damaged. They can have ...
Jul 3, 2024
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Antibodies can be likened to keys, with antigens as the corresponding locks. Each antibody is uniquely shaped to fit a specific antigen, much like a key fits its particular lock. The precise ability to bind to disease-causing ...
Jun 25, 2024
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A pioneering study published in the journal Nature Aging has unveiled significant heterogeneity in the risk factors affecting healthy aging in Latin America and emphasized the limitations of current models of brain health, ...
Jun 17, 2024
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An unsuspected gene, Glis2, has been found to be a target of polycystic kidney disease (PKD) signaling in preclinical models.
Jun 13, 2024
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A genetic disorder leads to an increase in bioactive lipids in the brain, resulting in an imbalance between excitation and inhibition in neural circuits and promoting mental disorders. However, treatment with an enzyme inhibitor ...
Jun 6, 2024
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As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
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In a scientific feat that broadens our knowledge of genetic changes that shape brain development or lead to psychiatric disorders, a team of researchers combined high-throughput experiments and machine learning to analyze ...
May 24, 2024
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A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.
May 23, 2024
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A research group led by University of Tsukuba has discovered a mouse pedigree that presents spontaneous sudden cardiac death attributed to inherited ventricular arrhythmia. This was identified through electrocardiographic ...
May 15, 2024
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