Medical research

Scientists find rare disease clues in cell's recycling system

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1). They found that a closely related compound will activate an enzyme, AMPK, triggering a cellular ...

Medical research

How healthy are you for your age?

On May 22, JoVE will publish details of a technique to measure the health of human genetic material in relation to a patient's age. The method is demonstrated by the laboratory of Dr. Gil Atzmon at New York's Albert Einstein ...

Diseases, Conditions, Syndromes

Computational methods reveal how hospital-acquired bacteria spread

Scientists at the Academy of Finland's Centre of Excellence in Computational Inference Research have developed novel computational methods that have yielded essential knowledge of how hospital-acquired bacteria spread and ...

Medical research

Study unveils insight into a debilitating brain disease

From the neurons that enable thought to the keratinocytes that make toenails grow–a complex canopy of sugar molecules, commonly known as glycans, envelop every living cell in the human body.

Medical research

Jammed molecular motors may play a role in the development of ALS

Slowdowns in the transport and delivery of nutrients, proteins and signaling molecules within nerve cells may contribute to the development of the neurodegenerative disorder ALS, according to researchers at the University ...

Cardiology

Discovery spurred by unique twist of fate

(Medical Xpress)—As people age, or as a result of poor nutrition, heart valves can become damaged by the accumulation of calcium deposits within the tissue. This calcification causes a thickening and hardening of the tissue ...

Oncology & Cancer

Study finds cancer-fighting goodness in cholesterol

A Simon Fraser University researcher is among four scientists who argue that cholesterol may slow or stop cancer cell growth. They describe how cholesterol-binding proteins called ORPs may control cell growth in A Detour ...

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