Genetics

No danger of cancer through gene therapy virus

In fall 2012, the European Medicines Agency (EMA) approved the modified adeno-associated virus AAV-LPL S447X as the first ever gene therapy for clinical use in the Western world. uniQure, a Dutch biotech company, had developed ...

Genetics

Gut microbes browse along a gene buffet

In the moist, dark microbial rainforest of the intestine, hundreds of species of microorganisms interact with each other and with the cells of the host animal to get the resources they need to survive and thrive.

Medical research

Host genome controls skin microbiota and inflammation

Numerous recent studies linked gut microbiota with various diseases such as obesity or diabetes. Little is known, however, on how gut and skin microbiota composition is controlled. In a recent study published in the journal ...

Genetics

Protein regulation linked to intellectual disability

Genetics researchers at the University of Adelaide have solved a 40-year mystery for a family beset by a rare intellectual disability – and they've discovered something new about the causes of intellectual disability in ...

Diseases, Conditions, Syndromes

Finding the genes that turn on Japanese encephalitis

Investigators have identified the specific genes that become overactive as a result of nerve cell infection with Japanese encephalitis virus. The genes activate cell receptors and signaling proteins that attract immune cells ...

Genetics

The gene machine

Scientists have discovered that the human body contains more than 25,000 genes, but what they do remains mostly a mystery. "We don't know the function of the vast majority of genes," says Nevan Krogan, PhD, director of the ...

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