A protein receptor called PAQR4 found within fat cells appears to act as a sensor for ceramides, waxy lipids whose overabundance has been linked to a variety of metabolic disorders and cancers, a study led by UT Southwestern ...
Jul 16, 2024
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New research indicates the inhibitory effects of cAMP responsive element binding protein 3 (CREB3) on hepatocellular carcinoma (HCC) in vitro and in vivo. The paper is published in the journal MedComm.
Jul 3, 2024
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A new study shows that hyperandrogenism—a key characteristic of polycystic ovary syndrome (PCOS)—affects immune cell populations in reproductive, metabolic and immunological tissues in a PCOS-like mouse model.
May 27, 2024
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Bromodomain-containing protein 7 (BRD7) was initially identified as a tumor suppressor, but further research has shown it has a broader role in other cellular processes, including the remodeling of chromosomes and cell cycle ...
May 1, 2024
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The hormone insulin controls many cellular processes and adapts them to the body's current energy supply. One of the insulin-regulated processes is the quality control of mitochondria in neurons, Angelika Harbauer and her ...
Mar 19, 2024
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The quintessential female sex hormone estrogen stimulates cells that line blood vessels to deliver insulin to muscles, lowering blood sugar and protecting against type 2 diabetes, UT Southwestern Medical Center researchers ...
Oct 23, 2023
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A new research study at the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology-Hellas (FORTH), published in the journal PNAS, reveals how cancer cell intrinsic mechanisms ...
Aug 10, 2023
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As the population ages, the number of people with neurodegenerative diseases, such as Alzheimer's disease, increases. Approximately 75,000 Canadians are diagnosed with Alzheimer's disease each year and experience a decline ...
Dec 14, 2022
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WEHI researchers in Melbourne have answered a 100-year-old question in diabetes research: can a molecule different to insulin have the same effect? The findings provide important insights for the future development of an ...
Dec 12, 2022
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Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks. That's ...
Oct 24, 2022
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