Researchers at the University of Copenhagen and the Copenhagen University Hospital have identified a particular genetic mutation that may cause parkinsonism in young people. The mutation interferes with the brain's transport ...
Jul 3, 2014
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Tooth decay is one of the most common chronic diseases worldwide. While oral hygiene and dietary choices promote tooth decay, genetics are also a factor in cavity formation.
Oct 27, 2014
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A recent study in the Journal of Investigative Dermatology describes the success of using lenabasum, a cannabinoid receptor type 2 (CB2) agonist that triggers the resolution of inflammation, to treat amyopathic dermatomyositis. ...
Sep 21, 2022
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Devastating neurodegenerative diseases like Huntington's, Alzheimer's, and Parkinson's are all associated with protein deposits in the brain, known as amyloid. Despite extensive research investment into the cause and toxicity ...
Jun 13, 2023
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Researchers at the University of Toronto and the Hospital for Sick Children (SickKids) are paving the way towards individualized medicine for patients with cystic fibrosis.
Aug 29, 2012
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It's well established that chronic inflammation can lead to colon cancer, but the molecular mechanisms behind this association aren't fully understood. Research at Vanderbilt University Medical Center into the role that the ...
Aug 19, 2019
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An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline ...
Sep 3, 2020
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Scientists still are not sure how neurological symptoms arise in COVID-19. Is it because SARS-CoV-2 infects the brain? Or are these symptoms the result of inflammation in the rest of the body? A study by Charité—Universitätsmedizin ...
Feb 16, 2024
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The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active ...
Jan 11, 2012
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The investigational drug vupanorsen reduced total levels of non-high-density lipoprotein (non-HDL) cholesterol by up to 28% in patients with high cholesterol who were already taking a cholesterol-lowering statin medication, ...
Apr 4, 2022
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