Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...
Apr 24, 2018
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Extracellular vesicles (EV) represent a promising vector system for biomolecules and drug delivery due to their natural origin and participation in intercellular communication. As the quantity of EVs is limited, the researchers ...
Apr 24, 2018
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Protein systems, such as Ras, make up the complex signaling pathways that control whether a cell divides or, in some cases, becomes cancerous and metastasizes into other regions of the body. For example, 98 percent of pancreatic ...
Feb 18, 2018
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The brains of patients with Alzheimer's disease contain characteristic tangles inside neurons. These tangles are formed when a protein called Tau aggregates into twisted fibrils. As a result, the neurons' transport systems ...
Nov 22, 2017
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Rift Valley fever virus, transmitted by mosquitoes, is responsible for outbreaks in livestock in Africa and can also be fatal in humans. Scientists from the Institut Pasteur and the CNRS, working with the University of Göttingen, ...
Nov 10, 2017
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Calcium-ATPases convey calcium ions (Ca2+) from the cytoplasm to the extracellular space via active transport (using ATP as an energy source), and thus fundamentally contribute to the control of a wide variety of Ca2+-dependent ...
Oct 20, 2017
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The contact areas between nerve cells are called synapses. What happens there lies at the heart of communication between nerve cells. Communication starts with the release of chemical messengers known as neurotransmitters ...
Sep 4, 2017
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A gene called triggering receptor expressed on myeloid cells 2, or TREM2, has been associated with numerous neurodegenerative diseases, such as Alzheimer's disease, Frontotemporal lobar degeneration, Parkinson's disease, ...
Aug 30, 2017
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Researchers have shown that a recently identified protein, called Speedy A, plays an essential role in the early stages of meiosis—a special type of cell division that produces sperm and egg cells.
May 17, 2017
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Researchers studying the root cause of cystic fibrosis have made a major advance in our understanding of silent gene changes with implications for the complexity of cystic fibrosis. The findings are published today in [16 ...
May 17, 2017
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