Medical research

3-D bioPen: A hydrogel injection to regenerate cartilage

Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage ...

Medical research

The art of building bone

Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicates the emerging role of chondrocyte-to-osteoblast ...

Arthritis & Rheumatism

3-D bioprinting constructs for cartilage regeneration

Cartilage injury is a common cause of joint dysfunction and existing joint prostheses cannot remodel with host joint tissue. However, it is challenging to develop large-scale biomimetic anisotropic constructs that structurally ...

Medical research

Can inhaled stem cells fix your brain?

(Medical Xpress)—In certain neurosurgical procedures, like fixing pituitary glands, surgeons can remove a tumor through the nose with minimal damage to surrounding tissue. It turns out, that passing things in the other ...

Medical research

Intervening to stop bone loss

Bone remodeling in the body involves a balancing act between osteoblasts, cells that build bone, and osteoclasts, cells that break it down. Diseases such as osteoporosis, arthritis, and periodontitis involve bone loss, and ...

Medical research

For large bone injuries, it's Sonic hedgehog to the rescue

A USC Stem Cell study in npj Regenerative Medicine presents intriguing evidence that large bone injuries might trigger a repair strategy in adults that recapitulates elements of skeletal formation in utero. Key to this repair ...

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