A multidisciplinary team of researchers has eliminated fatal mitochondrial DNA mutations in stem cells from patients with mitochondrial diseases. The study is published in a recent online issue of Nature as a collaboration ...
Jul 24, 2015
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For thousands of women around the globe carrying a mitochondrial disease, having a healthy child can be a gamble. This set of diseases affect mitochondria, tiny powerhouses that generate energy in the body's cells and are ...
Apr 23, 2015
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Mitochondrial diseases are maternally inherited genetic disorders that cause a wide spectrum of debilitating conditions and which currently have no cure. In a study published April 23 in the journal Cell, Salk Institute researchers ...
Apr 23, 2015
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Diseases caused by genetic mutations in the mitochondria – the powerhouses of the cell – can be disabling, or even deadly. That is why mitochondrial replacement therapy (MRT), otherwise also known as three-person IVF ...
Feb 2, 2015
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(Medical Xpress)—In a recent post we traced mechanisms of mitochondrial quality control in the nervous system back to their origins in the womb, and hinted that there would soon be more to come on this topic. Conveniently, ...
New work by a pioneering scientist details how subtle changes in mitochondrial function may cause a broad range of common metabolic and degenerative diseases. Mitochondria are tiny energy-producing structures within our cells ...
Oct 22, 2014
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The discovery of a "maternal age effect" by a team of Penn State scientists that could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells—and the transmission of these mutations to ...
Oct 13, 2014
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(Medical Xpress)—For several years, a class of anti-diabetic drugs known as biguanides, has been associated with anti-cancer properties. A number of retrospective studies have shown that the widely used diabetes drug metformin ...
Mar 17, 2014
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Patients with nephritic syndrome exhibit an array of symptoms that are associated with loss of kidney function, including excess protein in urine, swelling, and albuminuria. Many nephritic syndrome patients respond well to ...
Nov 25, 2013
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(Medical Xpress)—Three evolutionary biologists with ties to research facilities in the U.K., Germany and Australia have published a Policy Forum piece in the journal Science suggesting that governmental agencies slow the ...
