Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.
Jun 12, 2024
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Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease marked by the thickening and scarring of lung tissue with unclear etiology. Affecting around five million people worldwide, IPF causes severe respiratory ...
Jun 12, 2024
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As prostate cancer progresses, it becomes increasingly aggressive and can metastasize. In this form, the tumor is difficult to treat, which is reflected in high mortality rates: Worldwide, the malignant disease of the prostate ...
Jun 5, 2024
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As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
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Phenotypic plasticity is a cancer hallmark, and lung adeno-to-squamous transition (AST) triggered by LKB1 inactivation is significantly associated with drug resistance. Clinical data show that squamous transition occurs in ...
Jun 5, 2024
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In a proof-of-concept study, researchers at the National Institutes of Health (NIH) have developed an artificial intelligence (AI) tool that uses routine clinical data, such as that from a simple blood test, to predict whether ...
Jun 3, 2024
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Animal testing has long been a fixture of medical and pharmaceutical research, but alternative methods are growing more and more important. Innovative methods allow for research aimed directly at humans—without using animal ...
Jun 3, 2024
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An Oregon Health & Science University-developed platform for cytomegalovirus-based vaccines shows promise as a "shield" against cancer. The findings were recently published in the journal Science Advances.
May 29, 2024
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Cancer poses significant challenges due to the development of resistance and the likelihood of relapse. Resistance may arise from permanent genetic changes in cancer cells or non-genetic alterations in cancer cell behavior ...
May 28, 2024
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A new study shows that hyperandrogenism—a key characteristic of polycystic ovary syndrome (PCOS)—affects immune cell populations in reproductive, metabolic and immunological tissues in a PCOS-like mouse model.
May 27, 2024
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