A notable characteristic of several neurodegenerative diseases, such as Alzheimer's and Parkinson's, is the formation of harmful plaques that contain aggregates—also known as fibrils—of amyloid proteins. Unfortunately, ...
Aug 4, 2020
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Psoriasis, a chronic skin condition that causes itchy, red, scaly patches, afflicts more than 8 million Americans and 125 million people worldwide. Small molecule-based drugs like steroids can penetrate the skin to treat ...
Jul 22, 2020
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A global race is underway to discover a vaccine, drug, or combination of treatments that can disrupt the SARS-CoV-2 virus, which causes the COVID-19 disease, and prevent widespread deaths.
Apr 22, 2020
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In hopes of developing a possible treatment for COVID-19, a team of MIT chemists has designed a drug candidate that they believe may block coronaviruses' ability to enter human cells. The potential drug is a short protein ...
Mar 30, 2020
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People around the world are isolating themselves to help slow the spread of COVID-19. But there is another way those confined to their homes—but connected online—can join the fight against the novel coronavirus. Among ...
Mar 23, 2020
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Each cell in the human body holds a full two meters of DNA. In order for that DNA to fit into the cell nucleus—a cozy space just one hundredth of a millimeter of space—it needs to be packed extremely tight.
Jan 8, 2020
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Antibodies play a crucial role in our immune system by linking antigen recognition with complement activation for attacking foreign cells. Using high-speed atomic force microscopy, collaborative groups, including researchers ...
Jan 6, 2020
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Researchers at the University of Delaware, working with colleagues at Indiana University, have gained new insights into the virus that causes hepatitis B—a life-threatening and incurable infection that afflicts more than ...
Jun 1, 2018
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The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of POMC neurons in the hypothalamus that detect and integrate signals related to the body's energy state and ...
Jun 8, 2017
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A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process.
Nov 3, 2016
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