Diseases, Conditions, Syndromes

Tuberculosis bacteria trigger cough, facilitating spread

The bacteria that cause the deadly lung disease tuberculosis appear to facilitate their own spread by producing a molecule that triggers cough, a new study led by UTSW researchers shows. The findings, published online March ...

Immunology

Immune system targets vitamin B12 pathway to neutralize bacteria

Close to 1.8 billion people worldwide are infected with Mycobacterium tuberculosis (Mtb), the common and occasionally deadly bacterium that causes millions of cases of tuberculosis each year. The bacteria, having coevolved ...

Medications

Why does tuberculosis find a 65-year-old drug so hard to resist?

Since its discovery in 1954, there have been almost no recorded cases of tuberculosis becoming resistant to the antibiotic drug D-cycloserine (DCS) in patients. With resistance to many other drugs on the rise, a team of ...

Diseases, Conditions, Syndromes

To fight tuberculosis infection, early protection is crucial

In the first days after the tuberculosis (TB) bacteria infect the body, a flurry of immune cells are activated to fight the infection. Now, researchers have identified a master cell that coordinates the body's immune defenses ...

Parkinson's & Movement disorders

Link between tuberculosis and Parkinson's disease discovered

The mechanism our immune cells use to clear bacterial infections like tuberculosis (TB) might also be implicated in Parkinson's disease, according to a new collaborative study led by scientists from the Francis Crick Institute ...

Medical research

Molecular doorstop could be key to new tuberculosis drugs

Tuberculosis, which infects roughly one quarter of the world's population and kills nearly two million people a year, is not only deadly but ancient: signs of the disease have been found in Egyptian mummies. Despite its age, ...

Diseases, Conditions, Syndromes

Gastric acid suppressant lansoprazole may target tuberculosis

A cheap and widely used drug, used to treat conditions such as heartburn, gastritis and ulcers, could work against the bacteria that cause tuberculosis (TB), according to new research from UCL and the London School of Hygiene ...

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