Immunomodulatory drugs, including the Contergan derivatives lenalidomide and pomalidomide, have significantly improved the therapy of hematologic malignancies such as multiple myeloma. Researchers at the Technical University ...
Feb 12, 2021
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Salk Institute scientists have discovered that an interaction between two key proteins helps regulate and maintain the cells that produce neurons. The work, published in Cell Stem Cell on September 14, 2017, offers insight ...
Sep 14, 2017
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(Medical Xpress) -- The multidrug transporter EmrE functions as an asymmetric antiparallel dimer (molecule with two subunits). Drug (blue) transport from the inside to the outside of the cell membrane is accomplished by exchange ...
Jan 31, 2012
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Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell ...
Jul 9, 2013
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A University of Toronto research team has discovered new details about a key gene involved in ALS, perhaps humanity's most puzzling, intractable disease.
Jul 15, 2015
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Researchers from the National Institutes of Natural Sciences and Nagoya City University have achieved a significant breakthrough by elucidating the structure of amyloid β (Aβ) bound to glycolipids on the surface of nerve ...
Aug 7, 2023
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Researchers have shown that a recently identified protein, called Speedy A, plays an essential role in the early stages of meiosis—a special type of cell division that produces sperm and egg cells.
May 17, 2017
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The sustained presence in the nucleus of the protein known as Rac1 produces changes in nuclear morphology that are important in several biological processes, including malignant cancer. This is the finding of the research ...
Jan 29, 2015
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Studying a protein that gives structure to the nucleus of cells, Johns Hopkins researchers stumbled upon mutations associated with familial partial lipodystrophy (FPLD), a rare disease that disrupts normal patterns of fat ...
Mar 20, 2013
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Fresh insights into how our cells control muscle development could aid understanding of muscular dystrophy and other inherited diseases.
Jun 2, 2016
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