Oncology & Cancer

Scientists spot genes that make some sarcomas less aggressive

Scientists at Rice and Duke universities have identified a set of genes they say make sarcoma cells less aggressive. They hope to turn the discovery into new therapeutic approaches to fight metastatic cancers.

Genetics

Focusing in on high-resolution network biology

A central challenge in genetics is to understand how changes in DNA result in observable changes in an organism; how genotype maps to phenotype. As genes and their protein products do not act in isolation, connecting genotype ...

Pediatrics

Earlier adiposity rebound linked to metabolic syndrome

(HealthDay)—The age of adiposity rebound (AR), at which time body mass index (BMI) starts to rise after infancy, is associated with future development of metabolic syndrome, according to a study published online Dec. 23 ...

Medical research

Mouse mutant opens new path for birth defect research

(Medical Xpress)—According to the Centers for Disease Control, nearly 3 of every 100 babies in the U.S. are born with a birth defect. Among boys, one of the most common defects is the displacement of the urethral opening ...

Arthritis & Rheumatism

Novel susceptibility loci identified for osteoarthritis

(HealthDay) -- Five novel single nucleotide polymorphisms (SNPs) are significantly associated with osteoarthritis, including one near the nucleostemin-encoding gene, according to a study published online July 3 in The Lancet.

Cardiology

Specific phenotype relevant in subclinical primary aldosteronism

(HealthDay)—A suppressed renin phenotype is associated with higher incidence of incident hypertension than other plasma renin activity (PRA) phenotypes, according to a study published online Oct. 9 in the Annals of Internal ...

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