Oncology & Cancer

PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer

Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...

Oncology & Cancer

Major study stops bladder cancer from metastasizing to lungs

The diagnosis of localized bladder cancer carries an 80 percent five-year survival rate, but once the cancer spreads, the survival rate at even three years is only 20 percent. A major study published today in the Journal ...

Oncology & Cancer

Gene-based test identifies poor-prognosis colon cancers

(HealthDay) -- A sensitive and specific gene-based classifier can be used to identify BRAF mutant colon cancer tumors and a subpopulation of BRAF wild-type tumors with poor prognosis, according to a study published March ...

Oncology & Cancer

Intratumor heterogeneity seen in renal carcinomas

(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study published in ...

Oncology & Cancer

Researchers uncover new operations of cancer suppressor

(Medical Xpress) -- Scientists at the University of Dundee studying an important tumour suppressor, which is involved in at least a quarter of all cancers, have uncovered new ways in which it works.

Oncology & Cancer

Potential new target for colorectal cancer treatment

Researchers have identified a protein called PFDN6 that may play a role in the development and spread of colorectal cancer (CRC). The study, published in [journal name], found that PFDN6 levels are increased in CRC patients ...

Oncology & Cancer

Unraveling the link between the microbiome and esophageal cancer

Esophageal cancer (EC) is an aggressive malignancy with a poor prognosis, with its development and progression potentially influenced by changes in the esophageal microbiome. Recent studies have revealed that specific microbiome ...

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