In the most systematic and rigorous study conducted thus far in its field, the prion protein (PrPC) was clearly shown to play a role in preventing the onset of epileptic seizures. PrPC is perhaps best known in its 'degenerate' ...
Jul 9, 2015
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Prions are fascinating, enigmatic, and might teach us not only about rare prion diseases like Creutzfeld-Jakob disease, mad cow disease, or scrapie, but also about other more common neurodgenerative diseases. Two studies ...
Jul 2, 2015
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Research from Eric Kandel's lab at Columbia University Medical Center (CUMC) has uncovered further evidence of a system in the brain that persistently maintains memories for long periods of time. And paradoxically, it works ...
Jul 2, 2015
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Chronic wasting disease (CWD)—an infectious disease caused by prions—affects North American elk and deer, but has not been observed in humans. Using a mouse model that expresses an altered form of the normal human prion ...
Feb 23, 2015
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Botching a few folds might transform an origami cow into a deer or sheep. When cellular proteins do the same, they can trigger fatal neurodegenerative diseases that turn the brains of these mammals into dysfunctional sponges.
Feb 23, 2015
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The cellular prion protein (PrPC) has the ability to protect the brain's neurons. Although scientists have known about this protective physiological function for some time, they were lacking detailed knowledge of the molecular ...
Dec 17, 2014
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The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease – linked to the consumption of infected cattle meat – has been detected in the urine of patients with the disease by researchers ...
Aug 7, 2014
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Getting to the bottom of Alzheimer's disease has been a rapidly evolving pursuit with many twists, turns and controversies. In the latest crook in the research road, scientists have found a new insight into the interaction ...
Apr 23, 2014
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Prions are infectious agents responsible for neurodegenerative diseases such as bovine spongiform encephalitis (commonly known as "mad cow disease") and Creutzfeldt–Jakob disease in humans.
Mar 24, 2014
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Prions can be notoriously destructive, spurring proteins to misfold and interfere with cellular function as they spread without control. New research, publishingin the open access journal PLOS Biology on February 11 2014, ...
Feb 11, 2014
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