Oncology & Cancer

Mechanism explains breast cancer cell plasticity

One of the main obstacles to successfully treating breast cancer is the cells' ability to change in ways that make them resistant to treatment. Understanding the cellular mechanisms that mediate this cancer cell plasticity ...

Oncology & Cancer

Hidden signs in cancer tissue

When scientists at ETH Zurich analysed very large amounts of genetic cancer data, they found previously unresearched molecular changes. These could help in developing new personalised cancer treatments.

Medical research

Alternative splicing is crucial to muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

Genetics

G-quadruplex regulates breast cancer-associated gene

For breast cancer, carrying protein CD44s, instead of CD44v, has a survival advantage. Researchers have now discovered a mechanism by which cells can regulate switching between the two proteins, opening options for the development ...

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