Medical research
Scientists uncover mechanism that propels liver development after birth
Any expectant mother will tell you that she wants her baby's organs to develop properly in the womb.
Nov 4, 2015
6
70
Page 6 - News tagged with splicing
Oncology & Cancer
Research connects specific variations in RNA splicing with breast cancer causation
Researchers have identified cellular changes that may play a role in converting normal breast cells into tumors. Targeting these changes could potentially lead to therapies for some forms of breast cancer.
Oct 1, 2015
3
60
Genetics
Scientists discover tiny gene fragments linked to brain development and autism
Very small segments of genes called "microexons" influence how proteins interact with each other in the nervous system, scientists at the University of Toronto have found, opening up a new line of research into the cause ...
Dec 18, 2014
0
0
Neuroscience
Fruit fly lights up brain wiring
(Medical Xpress)—Fluorescent fruit flies have helped University of Queensland researchers take a critical step toward understanding the human brain's neuronal "wiring" and how it can go awry.
Oct 30, 2014
8
0
Medical research
How pairs of proteins collaborate to splice RNAs into cell-specific products
A team of scientists led by RIKEN researcher Yutaka Muto, in collaboration with Hidehito Kuroyanagi of Tokyo Medical and Dental University and Masatoshi Hagiwara of Kyoto University, has revealed some of the mechanisms that ...
Oct 17, 2014
3
0
Neuroscience
Neurons at work: Research provides a clearer view of 'alternative splicing'
Film editors play a critical role by helping shape raw footage into a narrative. Part of the challenge is that their work can have a profound impact on the finished product—with just a few cuts in the wrong places, comedy ...
Aug 12, 2014
0
0
Medical research
Orally delivered compounds selectively modify RNA splicing, prevent deficits in SMA models
Today the journal Science published results of a preclinical study demonstrating that treatment with orally available RNA splicing modifiers of the SMN2 gene starting early after birth is preventing deficits in a mouse model ...
Aug 7, 2014
0
0
Oncology & Cancer
Researchers discover 'master regulator' role for little-known protein in cancer cells
Researchers in the UNC School of Medicine found that the protein DAZAP1 plays a key role in the regulation of many genes through a process known as alternative splicing, and when highly expressed in cancer cell line experiments, ...
Apr 29, 2014
0
0
Medical research
Protein expression gets the heart pumping
Most people think the development of the heart only happens in the womb, however the days and weeks following birth are full of cellular changes that play a role in the structure and function of the heart. Using mouse models, ...
Apr 22, 2014
0
0
Medical research
Scientists uncover image of muscular dystrophy defect and design targeted drug candidates
Scientists from the Florida campus of The Scripps Research Institute have revealed an atomic-level view of a genetic defect that causes a form of muscular dystrophy, myotonic dystrophy type 2, and have used this information ...
Jan 2, 2014
0
0
