Alzheimer's: Newly identified protein pathology impairs RNA splicing
Move over, plaques and tangles.
Sep 10, 2013
1
0
Move over, plaques and tangles.
Sep 10, 2013
1
0
For the first time, scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified small molecules that allow for complete control over a genetic defect responsible for the most common adult onset ...
Jun 28, 2013
0
0
An international team of researchers – led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, ...
May 31, 2013
0
0
(Medical Xpress)—Researchers have found that missteps in a basic cellular process, RNA splicing, is the culprit behind a class of rare neurological disorders manifested by intellectual disability and stunted development.
Mar 29, 2013
0
0
Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – ...
Jan 17, 2013
0
0
Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells – abundantly found in connective tissues – into functional neurons. The findings, which could have far-reaching implications ...
Jan 10, 2013
0
0
(Medical Xpress)—A team of researchers, led by scientists at the University of Rochester, has identified a location in a gene of the influenza A virus that could be used as a "switch" for disrupting replication of the virus. ...
Aug 27, 2012
0
0
Cardiomyopathy comprises a deterioration of the heart muscle that affects the organ's ability to efficiently pump blood through the body. Previously researchers have tied forms of the disease to the alternative splicing of ...
Apr 1, 2012
0
0
(Medical Xpress) -- Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a universally fatal neurodegenerative disease. Mutations in two related proteins, TDP-43 and FUS, cause some forms of ALS. Specifically, ...
Nov 15, 2011
0
0
(Medical Xpress) -- University of Michigan researcher Gabrielle Rudenko and her Life Sciences Institute lab have solved the structure of a protein that is implicated in a number of neuropsychiatric disorders including autism ...
Jul 8, 2011
0
0