A delicate balance during brain development could have profound implications for understanding and treating medulloblastoma, the most common malignant brain tumor affecting children.
Mar 29, 2018
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Researchers at the Children's Medical Center Research Institute (CRI) at UT Southwestern have discovered that cells in the liver with whole genome duplications, known as polyploid cells, can protect the liver against cancer. ...
Feb 9, 2018
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Pancreatic cancer is a form of cancer associated with the highest mortality rates in the world. Genetic changes that could explain its aggressiveness and early metastasis are elusive. A team at Technical University of Munich ...
Jan 31, 2018
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Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction. The study, which will be published December 21 in the Journal of Cell Biology, suggests ...
Dec 21, 2017
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Tumor protein p53 is one of the most critical determinants of the fate of cancer cells, as it can determine whether a cell lives or dies in response to stress. In a new study published today in the journal Nature Communications, ...
Dec 13, 2017
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A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017.
Dec 8, 2017
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A team from Technical University of Munich has discovered an "emergency shut-off switch" in immune system T cells. Their results could lead to new therapies against T cell non-Hodgkin's lymphoma triggered by defective immune ...
Dec 6, 2017
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So-called "triple-negative" breast cancer is a particularly aggressive and difficult-to-treat form. It accounts for only about 10 percent of breast cancer cases, but is responsible for about 25 percent of breast cancer fatalities.
Nov 20, 2017
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If it burns in a house smoke detectors alert us hence protecting life. A molecular smoke alert has now been developed by Dresden researchers for the TP53 gene, the most important human cancer gene. The alert goes on if the ...
Nov 14, 2017
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Researchers from The Wistar Institute discovered a novel form of crosstalk among tumor cells and other cell types in the tumor microenvironment, elucidating the mechanism of action of an immunotherapeutic strategy that inhibits ...
Nov 13, 2017
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