In a paper published Tuesday in the journal eLife, Michael Francis, PhD, and colleagues highlight a new role for the protein NRX-1, a synaptic organizer in the nervous system of the nematode C. elegans.
Jul 30, 2018
0
39
Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity. Known as inhibitory synapses, these neural connections are rebalanced so that we can consolidate new information ...
Nov 1, 2022
0
75
When we think of the brain, we often think of the amazing things it is capable of—from conjuring up wild dreams to mastering foreign languages. At the same time, we may also think of devastating neurological diseases like ...
Jan 26, 2016
0
39
Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to go awry in both autism ...
May 2, 2016
0
6
A new small-molecule drug produced a rapid antidepressant response similar to that of ketamine when tested in mice, a new Yale-led study published April 16 in the Journal of Clinical Investigation shows.
Apr 17, 2019
0
18
A family of naturally occurring plant compounds could help prevent or delay memory loss associated with Alzheimer's disease, according to a new study by the Translational Genomics Research Institute (TGen).
May 26, 2011
0
0
A team of neuroscientists has identified a modification to a protein in laboratory mice linked to conditions associated with Alzheimer's Disease. Their findings, which appear in the journal Nature Neuroscience, also point ...
Aug 11, 2013
0
0
Synapse development is promoted by a variety of cell adhesion molecules that connect neurons and organize synaptic proteins. Many of these adhesion molecules are linked to neurodevelopmental disorders; mutations in neuroligin ...
Jan 28, 2013
0
0
Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer's disease (AD), a key step toward eventually ...
May 5, 2021
0
77
Northwestern Medicine scientists have discovered a new cause of Parkinson's disease—mutations in a gene called TMEM230. This appears to be the third gene definitively linked to confirmed cases of the common movement disorder.
Jun 6, 2016
0
18
