Titin is a "titanically large" protein—the largest in the human body—which enables elastic movements of our muscles, including the heart. Mutations in the titin gene (TTN) that impair this function are the most frequent ...
Nov 5, 2021
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Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), in collaboration with an international scientific team, have described a new mechanism of modulation of the mechanical properties of the heart, ...
Apr 27, 2022
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Although scientists have long speculated that a protein named titin measures thick filaments—the proteins that make muscles contract—no one has been able to provide evidence to support their theories.
Nov 14, 2017
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A University of Arizona doctoral candidate has shown for the first time that genetic mutations in the titin gene can cause skeletal muscle myopathy, a disease in which muscle fibers do not function properly, resulting in ...
Jan 27, 2014
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A healthy heart beats 50 to 100 times a minute and pumps 8,000 liters of blood around our body every day. A precondition for this function is the elasticity of the cardiac walls, which dilate as blood flows in (diastole) ...
Sep 15, 2020
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Critical illness myopathy (CIM) has taken on a new relevance as a result of the corona virus. CIM is the specialists' term for a muscle weakness which occurs in patients being treated in intensive care for a longer period ...
Sep 9, 2020
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Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and Columbia University in New York have discovered an important mechanism in the regulation of a protein that plays an essential role ...
Jan 12, 2018
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