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Genetics
Deep learning uncovers gene targets and potential drugs to slow brain aging
In a new study reported in Science Advances, scientists analyzed MRI data stored at the UK Biobank and identified seven genes responsible for fast biological brain aging and 13 existing drugs that can target those genes.
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Medical research news
Ebola-infected monkeys cured with a pill, sparking human treatment hopes
Monkeys infected with Ebola can be cured with a pill, according to a new study out Friday that could pave the way for more practical, affordable treatments in humans.
Mar 15, 2025
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Study uncovers developmentally distinct neural architectures controlling avoidant behaviors
Over the course of their lives, humans and other animals typically learn to avoid situations and stimuli that are dangerous or are perceived as threatening. Past neuroscience studies have gathered evidence suggesting that ...
Scientists discover how to reactivate cancer's molecular 'kill switch'
Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film. By selecting which scenes to keep and which to leave out, the editor can produce ...
Mar 14, 2025
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New AI model can estimate a person's true biological age from five drops of blood
We all know someone who seems to defy aging—people who look younger than their peers despite being the same age. What's their secret? Scientists at Osaka University (Japan) may have found a way to quantify this difference. ...
Mar 14, 2025
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How to prevent chronic inflammation from zombie-like cells that accumulate with age
In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.
Mar 14, 2025
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Two brain areas compete for control of memories, optogenetics study shows
Researchers at Ruhr University Bochum, Germany, have studied the impact of two brain areas on the nature of memory content. The team from the Department of Neurophysiology showed in rats how the so-called locus coeruleus ...
Mar 14, 2025
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New members of the CDKL family of genes linked to neurodevelopmental disorders
CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures. However, the role the other four members of this family play in health and disease is unknown.
Mar 14, 2025
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Decreased levels of TDP-43 gene may be contributing to neurodegenerative diseases like Alzheimer's and ALS
In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer's disease, and the ...
Mar 14, 2025
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A metabolic 'switch' that could help stop the spread of pancreatic cancer
Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolic "switch" to help it spread, revealing a potential new treatment strategy for this highly aggressive ...
Mar 14, 2025
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Not knowing what to expect can make pain feel worse
When we accidentally touch something familiar, like a warm pan, our brains already know what feeling to expect and how much it might hurt. But if you were blindfolded and had no idea you were touching a warm pan, you'd feel ...
Mar 14, 2025
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Older adults might be more resistant to bird flu infections than children, research finds
Prior exposures to specific types of seasonal influenza viruses promote cross-reactive immunity against the H5N1 avian influenza virus, according to new research from the Perelman School of Medicine at the University of Pennsylvania. ...
Mar 14, 2025
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Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer
Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy ...
Mar 14, 2025
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Medical imaging experts better at solving optical illusions—study shows training can improve visual perception
Medical imaging experts are adept at solving common optical illusions, according to research from four UK universities, including the University of East Anglia.
Mar 14, 2025
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Blood tests suggest that social disadvantage can accelerate aging and increase disease risk
People with favorable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological aging than peers of the same age, finds a new study ...
Mar 14, 2025
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Photoacoustic imaging reveals new insights into how the brain learns new information
Wayne State University researchers are using photoacoustic imaging to observe brain activity and, in the process, discovering more about how it responds to different types of learning and experiences.
Mar 14, 2025
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Study highlights that less than 1% of people with firearm access engage in defensive use in any given year
Those with access to firearms rarely use their weapons to defend themselves, and instead are far more likely to be exposed to gun violence in other ways, according to a Rutgers Health study.
Mar 14, 2025
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Inflammation proteins linked to bone density changes over time
In one of the first studies of its kind, a team of researchers from Keck School of Medicine of USC has found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over ...
Mar 14, 2025
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Lower waist-to-hip ratio in midlife linked to longer lasting cognitive function
Researchers from Oxford University, University College London, and collaborating institutions across Germany, France, and the Netherlands, found that diet quality and waist-to-hip ratio during midlife are associated with ...
