Early menopause tied to greater type 2 diabetes risk

Early menopause tied to greater type 2 diabetes risk
Women who experience early menopause have a greater risk of type 2 diabetes, according to a study published online Dec. 10 in Diabetes Care.

(HealthDay)—Women who experience early menopause have a greater risk of type 2 diabetes, according to a study published online Dec. 10 in Diabetes Care.

Judith S. Brand, from the University Medical Center Utrecht in the Netherlands, and colleagues analyzed data from 3,691 postmenopausal case subjects with type 2 diabetes and 4,408 subcohort members included in the InterAct study, a prospective case-cohort study nested within the European Prospective Investigation into Cancer and Nutrition study.

The researchers found that, over a median follow-up of 11 years, relative to women with menopause at age 50 to 54 years, for women with menopause at ages younger than 40; 40 to 44; 45 to 49; and 55 years and older, the hazard ratios (HRs) for type 2 diabetes were 1.32 (95 percent confidence interval [CI], 1.04 to 1.69); 1.09 (95 percent CI, 0.90 to 1.31); 0.97 (95 percent CI, 0.86 to 1.10); and 0.85 (95 percent CI, 0.70 to 1.03), respectively. There was a higher with shorter reproductive life span (HR per SD lower reproductive life span, 1.06; 95 percent CI, 1.01 to 1.12). The effect was not significantly modified by , , or smoking.

"Early menopause is associated with a greater risk of type 2 diabetes," Brand and colleagues conclude.

One author disclosed receiving funding from .

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Clopidogrel after MI less effective in diabetes patients

Sep 05, 2012

(HealthDay)—Clopidogrel therapy following a heart attack does less to reduce the risk of death in patients with diabetes than in those without diabetes, according to a study published in the Sept. 5 issue ...

Depression found to increase risk of death in diabetes

Jun 01, 2012

(HealthDay) -- For patients with type 2 diabetes, depression is associated with an increased risk of all-cause mortality, regardless of previous cardiovascular disease, according to a study published online ...

Risk of rupture increases with size of cerebral aneurysm

Jun 28, 2012

(HealthDay) -- The natural course of unruptured cerebral aneurysms varies according to their size, location, and shape, according to a study published in the June 28 issue of the New England Journal of Me ...

Body fat linked to reduced fracture risk for women

May 02, 2012

(HealthDay) -- Higher body fat mass is associated with a reduced risk of fracture among women, but not men, according to a study published in the May issue of the Journal of Internal Medicine.

Recommended for you

New test helps diagnose type 1 diabetes

Aug 21, 2014

(HealthDay)—The U.S. Food and Drug Administration has approved a new test that may help doctors diagnose type 1 diabetes, the most common form diagnosed in children and adolescents.

User comments