Diet rich in unsaturated fat may up insulin sensitivity

June 14, 2013
Diet rich in unsaturated fat may up insulin sensitivity
A diet rich in unsaturated fat may increase insulin sensitivity in individuals who are at higher risk for cardiovascular disease, according to research published in the May issue of Diabetes Care.

(HealthDay)—A diet rich in unsaturated fat may increase insulin sensitivity in individuals who are at higher risk for cardiovascular disease, according to research published in the May issue of Diabetes Care.

Meghana D. Gadgil, M.D., M.P.H., of Johns Hopkins University in Baltimore, and colleagues enrolled 164 individuals with or stage 1 hypertension, without diabetes, in a randomized, controlled, three-period, crossover feeding study. The three diets studied were a carbohydrate-rich diet (similar to the [DASH] diet), a protein-rich diet (predominantly from plant sources), and an unsaturated fat-rich diet (mostly monounsaturated fat). The primary outcome was calculation of the quantitative check index (QUICKI), a validated measure of insulin sensitivity.

At baseline, the researchers noted a mean of 30.2 kg/m² and a mean QUICKI of 0.35. The increase in QUICKI (0.005) was significantly greater with the unsaturated fat-rich diet compared with the carbohydrate-rich diet. The protein-rich diet had no significant effect on insulin sensitivity compared with the carbohydrate-rich diet.

"Our analysis suggests that a diet rich in unsaturated fats, which is commonplace in Mediterranean-style diets, improves insulin sensitivity in a population at risk for cardiovascular disease," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Study affirms 'mediterranean diet' improves heart health

November 17, 2011

(Medical Xpress) -- A team of Johns Hopkins researchers has uncovered further evidence of the benefits of a balanced diet that replaces white bread and pasta carbohydrates with unsaturated fat from avocados, olive oil and ...

Do low-carb diets damage the kidneys?

May 31, 2012

Low-carbohydrate, high-protein diets—like the Atkins diet—have been popular among dieters for years. For just as long, experts have worried that such diets might be harmful to the kidneys. A study appearing in an ...

Improving obesity-induced insulin sensitivity

June 1, 2012

In recent years, a growing body of evidence has linked inflammation to the development of insulin resistance. In insulin resistance, the hormone insulin is less effective in promoting glucose uptake from the bloodstream into ...

Dietary PA/OA fat ratio may affect T2DM risk in women only

December 28, 2012

(HealthDay)—A diet low in palmitic acid (PA) and high in oleic acid (OA) improves insulin sensitivity and is associated with lower levels of markers of metabolic and oxidative stress in women only, according to a study ...

Gene variants link to insulin resistance based on diet

April 28, 2013

(HealthDay)—Variants of insulin receptor substrate 1 (IRS1) are associated with insulin resistance and metabolic syndrome, but only under particular dietary conditions, according to a study published online April 17 in ...

Weight loss diets improve renal function in obese

June 6, 2013

(HealthDay)—Low-fat, Mediterranean, and low-carbohydrate diets are similarly effective in improving renal function in moderately obese people with or without type 2 diabetes, according to a study published online May 20 ...

Recommended for you

Promising progress for new treatment of type 1 diabetes

July 30, 2015

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports, reveals that administration ...

Bacteria may cause type 2 diabetes

June 1, 2015

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers ...

'Crosstalk' gives clues to diabetes

June 15, 2015

Sometimes, listening in on a conversation can tell you a lot. For Mark Huising, an assistant professor in the Department of Neurobiology, Physiology and Behavior at the UC Davis College of Biological Sciences, that crosstalk ...

1 comment

Adjust slider to filter visible comments by rank

Display comments: newest first

alfie_null
not rated yet Jun 16, 2013
I wonder if any of the participants gained or lost weight during the study?

Cynically, I was wondering: how soon before we see Olive Oil pills on the market, but - too late, they're here already. I guess what someone needs to do is run a study of the effects of loading a Mediterranean diet on top of what ever junk some group is already consuming.

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.