Persistent liver inflammation in sufferers of chronic viral hepatitis is likely caused by interactions between pro-inflammatory immune cells in the liver and products from gut bacteria, according to new work involving A*STAR ...
Jan 16, 2018
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11
An immobile mutant zebrafish first described by scientists more than 20 years ago turns out to have defects in the same gene as people with a rare muscle-degenerating disorder called nemaline myopathy, an A*STAR study has ...
Oct 19, 2017
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4
Researchers at the Institute of Bioengineering and Nanotechnology (IBN) have developed a simple method of organizing cells and their microenvironments in hydrogel fibers. Their unique technology provides a feasible template ...
Aug 19, 2013
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When my team and I first learned about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19), we sprang into action, searching the literature to identify the gaps. In times of ...
May 14, 2020
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5
Bystander cells present in human lung and colorectal tumors could indicate how well a patient will respond to immunotherapy, an A*STAR-led study finds.
Jul 16, 2018
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10
Using self-cleaving peptides, A*STAR researchers have designed a vector that improves efficiency for monoclonal antibody production, offering potential for improved preclinical studies.
Sep 11, 2015
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13
Concerns over toxicity have constrained the clinical application of photoacoustic imaging—a new experimental technique used to detect tumors lurking among healthy cells. A*STAR researchers from the Singapore Bioimaging ...
Sep 24, 2014
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1
Mobile pieces of DNA can jump around in the human genome and exert powerful regulatory effects on neighboring genes at new insertion sites. The most common mobile genetic elements are known as LINE-1 retrotransposons and ...
Sep 10, 2014
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An attack of gout is said to be like your joint catching fire, and someone slamming it with a hammer to put out the flames. Now A*STAR researchers have identified how the build-up of monosodium urate (MSU) crystals in the ...
Sep 20, 2017
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Scientists at A*STAR's Genome Institute of Singapore (GIS) have developed a new technique that simplifies the task of identifying the precise DNA mutations that cause disease, which lays the groundwork for the development ...
Apr 6, 2015
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