News tagged with dna methylation
Researchers unravel the relation between DNA methylomes and obesity
In a highlighted paper published online in Nature Communications, researchers from Sichuan Agricultural University and BGI reported the atlas of DNA methylomes in porcine adipose and muscle tissues, providing a valuable epigen ...
Genetics
May 22, 2012 |
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DNA methylation level is marker of breast cancer risk
(HealthDay) -- Women with high levels of white blood cell (WBC) DNA methylation at the ATM loci have a significantly increased risk of breast cancer, regardless of family history or menopausal status, according ...
Cancer
May 11, 2012 |
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New technique could transform epigenetics research
(Medical Xpress) -- Collaboration between scientists at Cambridge University and the Babraham Institute have demonstrated a new technique that will significantly improve scientists' ability to perform epigenetics ...
Genetics
Apr 26, 2012 |
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Noninvasive stool test for colorectal cancer unaffected by variables
A study presented today by Mayo Clinic researchers at the American Association for Cancer Research (AACR) Annual Meeting 2012 in Chicago identified two genes that are optimal targets to be analyzed in a new noninvasive test ...
Cancer
Apr 03, 2012 |
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Genomic data on chronic lung disease made readily available on new website
The constant focus on customer needs that drives the design of everything from automobiles to personal computers has now been applied to a field traditionally immune to such concepts: the scientific study of disease.
Genetics
Mar 22, 2012 |
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Exercise changes your DNA
You might think that the DNA you inherited is one thing that you absolutely can't do anything about, but in one sense you'd be wrong. Researchers reporting in the March issue of Cell Metabolism, a Cell Press publication, have f ...
Genetics
Mar 06, 2012 |
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DNA tags key to brain changes in mental disorders
(Medical Xpress) -- Researchers from the Institute of Psychiatry at King’s College London have found a relationship between molecular tags on our DNA and the weight of a particular region of the human ...
Genetics
Feb 27, 2012 |
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Common flame retardant linked to social, behavioral and learning deficits
Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning ...
Genetics
Feb 16, 2012 |
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Gene regulator in brain's executive hub tracked across lifespan
For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key findings ...
Autism spectrum disorders
Feb 02, 2012 |
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research shows health inequalities imprinted on DNA
(Medical Xpress) -- New research from the University of Glasgow shows that the health of the city’s most deprived residents could be impaired before they are even born.
Medical research
Jan 24, 2012 |
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How protein networks stabilize muscle fibers: Same mechanism as for DNA
The same mechanism that stabilises the DNA in the cell nucleus is also important for the structure and function of vertebrate muscle cells. This has been established by RUB-researchers led by Prof. Dr. Wolfgang Linke (Institute ...
Genetics
Jan 23, 2012 |
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Inflammatory mediator promotes colorectal cancer by stifling protective genes
Chronic inflammation combines with DNA methylation, a process that shuts down cancer-fighting genes, to promote development of colorectal cancer, scientists at The University of Texas MD Anderson Cancer Center report today ...
Inflammatory disorders
Jan 22, 2012 |
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Orphaned children exhibit genetic changes that require nurturing parents
Children who experience the stress of separation at birth from biological parents and are brought up in orphanages undergo biological consequences such as changes in their genome functioning, Yale School of ...
Psychology & Psychiatry
Dec 05, 2011 |
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Environment and diet leave their prints on the heart
A University of Cambridge study, which set out to investigate DNA methylation in the human heart and the 'missing link' between our lifestyle and our health, has now mapped the link in detail across the entire human genome.
Medical research
Nov 29, 2011 |
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Controlling patterns of DNA methylation
A study performed by scientists in Dirk Schübeler's team at the Friedrich Miescher Institute for Biomedical Research in Basel identifies DNA sequences that autonomously determine DNA methylation patterns. ...
Genetics
Oct 28, 2011 |
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DNA methylation
DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the best characterized epigenetic mechanism. Because methylation is a common capability of all viruses for self non-self identification, the epigenetic code could be a persistent remnant of ancient viral infection events.
DNA methylation involves the addition of a methyl group to DNA — for example, to the number 5 carbon of the cytosine pyrimidine ring — in this case with the specific effect of reducing gene expression. DNA methylation at the 5 position of cytosine has been found in every vertebrate examined. In adult somatic tissues, DNA methylation typically occurs in a CpG dinucleotide context; non-CpG methylation is prevalent in embryonic stem cells.
In plants, cytosines are methylated both symmetrically (CpG or CpNpG) and asymmetrically (CpNpNp), where N can be any nucleotide but guanine.
Research has suggested that long term memory storage in humans may be regulated by DNA methylation.
For more information about DNA methylation, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
