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HIV & AIDS
A chain reaction: HIV vaccines can lead to antibodies against antibodies
Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.
4 hours ago
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Neuroscience
Specific neurons with an immune 'doorbell' may influence mood and memory
Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high levels of IL-1 in the brain are linked to neuroinflammation, which can disrupt ...
4 hours ago
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Medical research news
Retinal neurons provide insight into schizophrenia disease mechanisms
Researchers analyzed the genetic connection of retinal cells and several neuropsychiatric disorders. By combining different datasets, they found that schizophrenia risk genes were associated with specific neurons in the retina. ...
4 hours ago
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Sepsis molecule discovery could lead to improved treatments for critically ill patients
Researchers at Oregon Health & Science University have uncovered how a molecule found on certain bacteria may drive blood clotting in sepsis, a life-threatening condition that causes about 8 million deaths per year.
5 hours ago
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The power of cinema: Study shows film intervention reduces violence against children
A new study shows that screenings of a locally-produced narrative film about parenting led to a significant reduction in physical violence against children.
5 hours ago
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Suraxavir trial finds faster flu recovery times for male but not female users
A single 40-mg dose of the antiviral drug suraxavir marboxil significantly shortened flu symptom resolution time in male patients aged 5–65, according to research led by the China-Japan Friendship Hospital in China. Intriguingly, ...
Brain-controlled interface experiment provides empirical support for one-way neural activity paths
Neural network models that are able to make decisions or store memories have long captured scientists' imaginations. In these models, a hallmark of the computation being performed by the network is the presence of stereotyped ...
5 hours ago
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Genetically modified mice hint at tau hyperphosphorylation's early role in neurodegenerative diseases
Tau is a microtubule-associated protein that helps to stabilize the structure of neurons, specifically by supporting microtubules, cylindrical structures that contribute to cell motility, intracellular transport and the maintenance ...
Fluorescent probes illuminate cholesterol and Alzheimer's research
The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry ...
5 hours ago
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Neuroimaging reveals 94% of gray matter in brains of mothers undergoes changes during pregnancy
A study led by the UAB has analyzed the brains of women during pregnancy for the first time using neuroimaging techniques. The study included non-pregnant mothers, whose partners were pregnant, to distinguish biological effects ...
5 hours ago
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Key enzyme identified as potential target for cancer immunotherapy
Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme—P4HA1 prolyl hydroxylase, is strongly induced in CD8+ T cells in solid cancer, the primary immune cells involved in combating ...
6 hours ago
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Subjective sleep assessments are unreliable, in-home electroencephalography reveals
Researchers from University of Tsukuba have identified significant discrepancies between subjective and objective assessments of sleep.
7 hours ago
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Researchers propose novel model to screen misreporting in dietary surveys
An international team led by Prof. John Speakman from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences derived a predictive model by combining classical statistics and machine learning for ...
7 hours ago
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Brains of people with sickle cell disease appear older, study finds
Individuals with sickle cell disease—a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen delivery to organs—are at a higher risk for stroke and resulting cognitive disability. But even ...
7 hours ago
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Interdisciplinary research lays groundwork for predicting if bone cancer will spread
Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year shortly before being diagnosed with osteosarcoma, a type of cancer that starts in the bones. Although ...
4 hours ago
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Drug-discovery platform for high-risk leukemias in children shows promising results
Targeted therapies for high-risk leukemia in children have yet to be developed, but scientists at Université de Montréal and its affiliated Institute for Research in Immunology and Cancer are working on a large-scale drug ...
8 hours ago
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AI-driven approach reads heart cells' inner electrical signals from the outside
A team of researchers led by the University of California San Diego and Stanford University has developed a noninvasive method to monitor the electrical activity inside heart muscle cells from the outside, avoiding the need ...
9 hours ago
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Phase 2 results suggest continued study of novel first-line combo for advanced kidney cancer
In the open-label phase 2 LITESPARK-003 study, led by Dana-Farber Cancer Institute's Toni Choueiri, MD, researchers investigated for the first time the combination of cabozantinib, an anti-angiogenic agent, plus belzutifan, ...
5 hours ago
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Nutritional interventions found effective for hemodialysis patients, increasing energy intake
In recent years, advancements in dialysis therapy and the growing number of elderly patients starting dialysis have contributed to the aging of the overall dialysis population. Consequently, malnutrition-related conditions ...
7 hours ago
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Genetic reanalysis results in more than 500 patients receiving diagnosis
The European consortium for Solving the Unsolved Rare Diseases has demonstrated the significance of international collaboration to address the unmet medical needs for rare diseases' diagnosis. More than 500 European patients ...
13 hours ago
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