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Diseases, Conditions, Syndromes

Clinical trial demonstrates success in treating rare blood disorder

A clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than one in 5,000 people worldwide.

Medical research

Ground squirrel study points to potential development of a cataract drug

Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye's lens that occurs commonly in people as they age. ...

Medical research news

Genetics

Master copper regulator discovery may offer Alzheimer's clues

New therapeutic opportunities often emerge from research on simple organisms. For instance, the 2020 Nobel Prize in Chemistry awarded to Emmanuelle Charpentier, Ph.D., and Jennifer Doudna, Ph.D., for their CRISPR-based DNA ...

Neuroscience

New brain organoid model replicates human cortical domains

The group of Jürgen Knoblich at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences, has developed a new method that allows scientists to cultivate brain organoids with distinct cortical areas ...

Oncology & Cancer

Lowering cancer drug dose could open tumors to immunotherapy

Research undertaken at the Harry Perkins Institute of Medical Research in Perth has shown that administering anti-cancer drugs at a hundred-fold lower dose than standard protocols could improve the tumor's response to immunotherapy.

Medications

Weight loss drugs could help fight fatty liver disease

In the fight against fatty liver disease, researchers are looking for any and all possible solutions. But to combat the disease, which is also known as metabolic dysfunction-associated steatotic liver disease, or MASLD, scientists ...