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Oncology & Cancer
Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme's role
Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from IOCB Prague has now described in detail how cells repair this damaged genetic information.
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Genetics
Using both genetic information and AI to diagnose pneumonia could curb the overuse of antibiotics
Lung infections like pneumonia are among the world's top killers—but diagnosing them is notoriously hard. Now, researchers at UC San Francisco have found a way to identify these infections in critically ill patients by ...
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Medical research news
Multiple myeloma develops differently in men and women, study reveals
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have uncovered biological differences in how multiple myeloma develops and progresses in men and in women. The rare blood cancer occurs ...
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New antibody design blocks cytomegalovirus from hiding from the immune system
Researchers at Texas Biologics at The University of Texas at Austin, working with scientists internationally, have made an important discovery that could improve treatment of human cytomegalovirus (HCMV), a common but overlooked ...
29 minutes ago
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Occupational factors strongly influence long COVID risk, finds study
Work-related factors play a significant and independent role in the risk of developing long COVID, shows a new study based on the COVICAT cohort and led by the Barcelona Institute for Global Health (ISGlobal) in collaboration ...
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'Tubuloids' offer a realistic platform for modeling chronic kidney disease
Chronic kidney disease (CKD) is a progressive condition that begins with tissue damage and gradually leads to loss of kidney function. The condition, which affects about 10% of the global population, is difficult to study ...
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Psilocybin shows greater potential than cannabinoids for obsessive-compulsive disorder treatment
In a review of previous studies, McMaster University researchers observe a stronger signal for psilocybin as a treatment for obsessive-compulsive disorder than cannabinoids.
Mapping pre-myelinating oligodendrocytes: New mouse line links neuronal activity to cell survival
Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, which is essentially the brain's white matter, was believed to serve the main function of speeding ...
Researchers discover bias in AI models that analyze pathology samples
Pathology has long been the cornerstone of cancer diagnosis and treatment. A pathologist carefully examines an ultrathin slice of human tissue under a microscope for clues that indicate the presence, type, and stage of cancer.
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40% of MRI signals do not correspond to actual brain activity, study suggests
For almost three decades, functional magnetic resonance imaging (fMRI) has been one of the main tools in brain research. Yet a new study published in Nature Neuroscience fundamentally challenges the way fMRI data have so ...
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Why a mild brain injury can trigger Alzheimer's
New research from the University of Virginia School of Medicine is revealing why traumatic brain injury increases the chance of developing Alzheimer's disease—and the discovery is pointing to a potential strategy to prevent ...
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Ultrasound paired with vibrating nanoparticles softens tumor tissue, improving drug delivery
Cancer is one of the leading causes of death in the U.S., second only to heart disease. But a new cancer treatment method from CU Boulder researchers uses sound waves to soften tumors and could be a potent tool against the ...
5 hours ago
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Study finds combined gene mutations better mimic rare gut disorder in mice
During development of the digestive system, a complex network of nerves forms around it, creating a "second brain"—the enteric nervous system (ENS)—which controls the movement of food and waste through the gut. But a ...
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Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.
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Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'
Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.
7 hours ago
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New understanding of T cell receptors may improve cancer immunotherapies
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full ...
7 hours ago
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Structure of dopamine-releasing neurons relates to the type of circuits they form for smell-processing, study finds
Closely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical structure.
2 hours ago
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New video dataset captures human dynamics of care, advancing AI for health care
Researchers at the University of Pennsylvania have launched Observer, the first multimodal medical dataset to capture anonymized, real-time interactions between patients and clinicians. Much like the medical drama The Pitt, ...
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Who is more likely to get long COVID? New study uncovers genetic drivers behind the disease
Australian scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
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Reducing social isolation protects the brain in later life, study shows
New research from the University of St Andrews has discovered a direct causal effect between social isolation and a faster decline in later-life cognitive function. Pathological cognitive decline is most often driven by Alzheimer's ...
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