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Immunology

Battle fatigue can drive T cells to exhaustion: Cancer and viruses are tough to fight

Just as it is for marathoners who've completed a 26-mile run, or shrubs that have gone without water in a heatwave—exhaustion is an unavoidable fact of life. Dogs get exhausted after herding sheep; birds turn in for the ...

Neuroscience

Researchers ID location on brain protein linked to Parkinson's disease development

Johns Hopkins Medicine researchers say they have pinpointed the section of alpha-synuclein, a protein in the brain that causes it to latch onto brain cells called neurons and likely drives the development of Parkinson's disease, ...

Oncology & Cancer

Drug combination gets advanced liver cancer patients to surgery

A combination of the kinase-inhibitor drug cabozantinib and the immunotherapy drug nivolumab can make curative surgery possible in some liver cancer patients who would normally not be considered surgery candidates.

Medical research

Mice treated with this cytokine lose weight by 'sweating' fat

Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls, according to new research published Thursday in Science from researchers in the Perelman School of ...

Diseases, Conditions, Syndromes

Researchers show how air pollution may cause chronic sinusitis

Chronic rhinosinusitis (CRS) is a 12-week or longer condition during which the sinuses get infected or irritated, become swollen, are severely congested and secrete mucus into the throat. CRS also can cause facial pain, pressure ...

Medications

New cancer therapies that reduce the risk of heart damage

With modern-day cancer therapeutics presenting adverse side effects to heart health, scientists are studying methods to attack cancer cells without the risk of damaging the heart. Researchers Steven Townsend, associate professor ...

Biomedical technology

Tracking circadian rhythms from your smartwatch

Smartwatches are handy devices for people to keep track of the number of steps they take per day or to track their mile time during a run. But they are also opportunities for scientists to understand people's physiological ...

Neuroscience

Taking breaks while learning improves memory

We remember things longer if we take breaks during learning, referred to as the spacing effect. Scientists at the Max Planck Institute of Neurobiology gained deeper insight into the neuronal basis for this phenomenon in mice. ...

Diseases, Conditions, Syndromes

Combined effects of masking and distance on aerosol exposure potential

The Centers for Disease Control and Prevention (CDC) recommended this week that people vaccinated against COVID-19 resume wearing masks in public indoor spaces in areas of the United States where the virus is spreading. "Appropriate ...