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Alzheimer's disease & dementia
Some diabetes drugs tied to lower risk of dementia, Parkinson's disease
A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson's disease, according to a study published in the September 18, 2024, online issue of Neurology.
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Health
The MIND diet may lower the risk of memory problems later in life, study shows
People whose diet more closely resembles the MIND diet may have a lower risk of cognitive impairment, according to a study published in the September 18, 2024, online issue of Neurology. Results were similar for Black and ...
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Medical research news
New research finds higher levels of leptin indicate brain protection against late-life dementia
New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, ...
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Ground squirrel study points to potential development of a cataract drug
Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye's lens that occurs commonly in people as they age. ...
2 hours ago
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Tailoring radiation therapy for brain cancer treatment: A personal investigation
A University of Ottawa neuroscientist's personal battle with cancer has inspired new research geared toward tailoring radiation treatment to reduce damage to the brain. The research is published in the journal Scientific ...
2 hours ago
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Changes in chromosomes of cancer cells may increase their sensitivity to anti-cancer drugs
Two complementary studies from the Faculty of Medical and Health Sciences at Tel Aviv University, in collaboration with the European Institute of Oncology in Milan, have extensively examined the characteristics of cells with ...
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Molecular pathway discovery points to a way to modulate scarring in spinal cord injury
After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it. But over time, too much scarring can prevent nerves from regenerating, impeding ...
3 hours ago
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Breast and ovarian cancer newly linked to thousands of gene variants
Scientists have pinpointed thousands of genetic changes in a gene that may increase a person's risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalized care.
3 hours ago
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Researchers identify role of Parkinson's-related protein in cancer and T cell activation
A team from the Wistar Institute has demonstrated the role of Parkin—a protein implicated in Parkinson's disease—in the body's innate immune response to cancer. Parkin is not expressed in several cancers.
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Antiviral-resistant variants of SARS-CoV-2 can emerge in immunocompromised people
Individuals with compromised immunity and persistent COVID-19 infections can harbor drug-resistant variants of the SARS-CoV-2 virus, which have the potential to spread to the general population found researchers at Weill ...
3 hours ago
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Master copper regulator discovery may offer Alzheimer's clues
New therapeutic opportunities often emerge from research on simple organisms. For instance, the 2020 Nobel Prize in Chemistry awarded to Emmanuelle Charpentier, Ph.D., and Jennifer Doudna, Ph.D., for their CRISPR-based DNA ...
4 hours ago
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Serotonin-specific receptor that dampens incoming visual information discovered
A serotonin-specific receptor can determine how important visual stimuli are perceived. This explains the effects of certain drugs and could help in understanding psychiatric diseases.
4 hours ago
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New brain organoid model replicates human cortical domains
The group of Jürgen Knoblich at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences, has developed a new method that allows scientists to cultivate brain organoids with distinct cortical areas ...
4 hours ago
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Understanding changes in pre-clinical Alzheimer's disease: Study finds two proteins impact brain activity differently
Amyloid-beta and tau proteins have long been associated with Alzheimer's disease. The pathological buildup of these proteins leads to cognitive decline in people with the disease. How it does that, though, remains poorly ...
11 hours ago
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Weight loss drugs could help fight fatty liver disease
In the fight against fatty liver disease, researchers are looking for any and all possible solutions. But to combat the disease, which is also known as metabolic dysfunction-associated steatotic liver disease, or MASLD, scientists ...
4 hours ago
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Lowering cancer drug dose could open tumors to immunotherapy
Research undertaken at the Harry Perkins Institute of Medical Research in Perth has shown that administering anti-cancer drugs at a hundred-fold lower dose than standard protocols could improve the tumor's response to immunotherapy.
5 hours ago
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A transparent AI approach helps provide a more tailored cardiovascular risk assessment
Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability.
5 hours ago
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Study finds nonfatal opioid overdoses in youth spiked during pandemic: Majority occurred at home
Drug overdose mortality has risen faster among adolescents than the general population in recent years, largely due to fentanyl, a potent opioid pain medication. A study published in JAMA sheds light on trends in nonfatal ...
5 hours ago
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First academic study on slap fighting highlights risks to participants' neurological health
University of Pittsburgh School of Medicine experts analyzed visible signs of concussion in individuals participating in professional slap fighting competitions and reported the results in a paper published in JAMA Surgery.
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Preparing for widespread use of biomarkers to diagnose Alzheimer's disease
For years, many people with Alzheimer's disease have been diagnosed clinically and confirmed at autopsy. Now Alzheimer's disease pathology can be identified with relatively high accuracy via a blood test that has the potential ...
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