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Arthritis & Rheumatism

Study offers potential for early diagnosis and therapeutic intervention for rheumatoid arthritis

Currently, there are no cures for rheumatoid arthritis (RA), which affects 40,000 people in Ireland. The disease costs an estimated $22,000 per patient, per year with an overall cost to the health system of ~$608 million. ...

Arthritis & Rheumatism

AI chatbots rival doctors in accuracy for back pain advice, study finds

A new study reveals that artificial intelligence chatbots, such as ChatGPT, may be almost as effective as consulting a doctor for advice on low back pain.

Arthritis & Rheumatism

Study shows AFL players' hip issues begin in early career

Researchers from La Trobe University studied 58 pain-free male Australian Football League (AFL) draftees, finding that nearly half showed hip joint changes on Magnetic Resonance Imaging (MRI) and 20% had a particular hip ...

Arthritis & Rheumatism

Study uncovers key factors in myositis-induced muscle weakness

A study has shed new light on the mechanisms behind idiopathic inflammatory myopathies (myositis), a group of systemic autoimmune disorders known for causing severe muscle weakness, fatigue, and increased mortality.

Arthritis & Rheumatism

Machine learning helps identify rheumatoid arthritis subtypes

A machine-learning tool created by Weill Cornell Medicine and Hospital for Special Surgery (HSS) investigators can help distinguish subtypes of rheumatoid arthritis (RA), which may help scientists find ways to improve care ...

Arthritis & Rheumatism

Surprising mechanism of lupus kidney damage identified

A Berlin-led research team has uncovered critical regulators of severe kidney damage in patients with lupus, an autoimmune disorder affecting an estimated five million people worldwide, most of whom are young women. A small, ...

Arthritis & Rheumatism

Data suggest smoking doesn't impact RA treatment response

(HealthDay)—For patients with early rheumatoid arthritis (RA), smoking status does not impact treatment response to early combination therapy or initial methotrexate treatment with step-up therapy, according to a study ...

Arthritis & Rheumatism

Risk factors ID'd for revision of total hip replacement

(HealthDay)—Younger, taller, and heavier patients who undergo primary total hip replacement (THR) are at a greater risk of needing a revision surgery, according to research published in the December issue of Arthritis Care ...

Arthritis & Rheumatism

Predictors of organ damage identified in patients with SLE

(HealthDay)—Patient age, hypertension, and corticosteroid use are the most important predictors of the cumulative organ damage that occurs in patients with systemic lupus erythematosus (SLE), according to research published ...

Arthritis & Rheumatism

Immunogenicity strongly impacts response to adalimumab in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), long-term clinical outcomes are good with etanercept and adalimumab; but for adalimumab, treatment response is strongly dependent on the presence or absence of anti-adalimumab ...

Arthritis & Rheumatism

Arthritis cartilage shows mitochondrial dysfunction

(HealthDay)—Cartilage from osteoarthritis patients shows greater oxidative damage and mitochondrial dysfunction than healthy cartilage, which is associated with the downregulation of the superoxide dismutase 2 (SOD2) gene, ...

Arthritis & Rheumatism

Pulmonary complications often fatal in systemic JIA

(HealthDay)—Pulmonary complications are under-recognized in systemic juvenile idiopathic arthritis (sJIA), and are often fatal, according to a study published online Nov. 8 in Arthritis Care & Research.

Arthritis & Rheumatism

ACR: Strontium ranelate cuts progression of knee OA

(HealthDay)—The osteoporosis therapeutic strontium ranelate (SrRan) reduces radiographic and radiological progression of knee osteoarthritis, according to a study presented at the annual meeting of the American College ...

Arthritis & Rheumatism

Expensive arthritis treatment no better than steroid therapy

A randomized, double-blind clinical trial by researchers at Hospital for Special Surgery has revealed that corticosteroids are more effective than the more expensive treatment, hylan G-F 20 (Synvisc One, Genzyme Biosurgery), ...

Arthritis & Rheumatism

Rheumatoid arthritis patients can get gout too, study finds

Refuting a belief long held by many physicians, a Mayo Clinic study found that rheumatoid arthritis patients also can get gout. The research is among several studies Mayo Clinic is presenting at the American College of Rheumatology ...

Arthritis & Rheumatism

Xeljanz approved for rheumatoid arthritis

(HealthDay)—Xeljanz (tofacitinib) has been approved by the U.S. Food and Drug Administration to treat symptoms of rheumatoid arthritis (RA) among people who can't tolerate, or haven't been helped by, the drug methotrexate.

Arthritis & Rheumatism

Few PT interventions effective for knee osteoarthritis

(HealthDay)—Only a few physical therapy (PT) interventions are effective for knee pain secondary to osteoarthritis, specifically exercise and ultrasonography, according to a review published in the Nov. 6 issue of the Annals ...

Arthritis & Rheumatism

Keep moving to ease pain of knee arthritis, review says

(HealthDay)—Adults with painful osteoarthritis of the knee should turn to exercise—aerobic, aquatic or strength training—as a good nonsurgical way to ease their pain and improve their functioning, a new review suggests.

Arthritis & Rheumatism

Salivary gland ultrasonography improves Sjogren's diagnosis

(HealthDay)—The addition of salivary-gland ultrasonography (SGUS) to American-European Consensus Group (AECG) classification criteria improves the accuracy of diagnosis of primary Sjögren's syndrome (pSS), according to ...