Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood. Currently, there is no effective treatment or cure for MSMDS.
Sep 11, 2025
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Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed. Their findings, published in Circulation, could eventually ...
Jun 24, 2025
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Peri-implantitis (PI) is a chronic inflammatory disease that affects dental implants, posing challenges in management and exhibiting a high rate of recurrence. Current treatment for PI often mirrors that of periodontitis, ...
Dec 5, 2024
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A new research paper titled "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance" has been published ...
Feb 7, 2024
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RUDN University scientists have discovered that in weightlessness, the contractile activity of smooth muscles in the hollow organs of the gastrointestinal tract is disrupted. New data must be taken into account when planning ...
Jan 16, 2024
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A discovery of a mutation in the gene ACTA2 has given researchers, led by Dianna Milewicz, MD, Ph.D., with UTHealth Houston, insight into understanding the cause of a rare and progressive problem with arteries in the brain ...
Sep 28, 2023
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A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s—with normal cholesterol levels and no other risk factors—to develop coronary artery disease has been identified, according ...
Jul 7, 2023
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A team of investigators from Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB) and Mass General for Children (MGfC) has identified—for the first time—the mutation in a single non-coding ...
Feb 28, 2023
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