SYNGAP1 encephalopathy is a rare genetic disorder for which there is no treatment. It causes epilepsy, intellectual disability, psychomotor delay and, frequently, autism. It arises from mutations in the SYNGAP1 gene, which ...
Apr 22, 2026
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Autism spectrum disorder (ASD) is a neurodevelopmental condition estimated to affect approximately 1 in 100 children worldwide. This condition is characterized by differences in how people communicate and interact with others, ...
Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and robust gene reconstitution ...
Feb 3, 2026
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Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by differences in communication, behavior and the processing of sensory information. Past research has shown that some individuals diagnosed with ...
A team of researchers has identified for the first time the mechanism linking a mutation in the Shank3 gene with alterations in social behavior. Using a mouse model carrying this autism-associated mutation, the study shows ...
Sep 4, 2025
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From birth, human survival depends on the ability to engage with others. This ability, which is essential for development, seems to be impaired very early on in children with autism spectrum disorders (ASD), who show limited ...
Apr 14, 2025
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Our brains contain billions of neurons and trillions of connections, and scientists are only beginning to understand the intricate process required to build this level of complexity. This includes uncovering the role of microRNAs: ...
Apr 4, 2025
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A new study has revealed that Beagle dogs carrying mutations in the Shank3 gene—a high-risk gene for autism spectrum disorder (ASD)—exhibit face-processing abnormalities similar to those observed in human ASD patients.
Apr 3, 2025
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Northwestern Medicine investigators have developed a method to measure protein expression in an individual neuron, a discovery that will enable scientists to study how this process goes awry in disease, according to a study ...
Apr 8, 2024
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Researchers at the Hebrew University of Jerusalem and the University of Haifa in Israel have discovered that production of nitric oxide in the brain correlates with autistic symptoms. In their paper, "The NO Answer for Autism ...
