Cancer

Regulation and potential drug targets of tumor-associated Tregs

According to estimates from the World Health Organization (WHO), there will be 18.1 million new cases and 9.6 million cancer deaths worldwide in 2018. Cancer is a serious disease that affects people all over the world. And ...

Cancer

Unraveling the genetic causes of skin cancer

Skin cancer is on the rise in the United States. Squamous cell carcinoma, the second most common form of cancer in the U.S., has the highest mortality rate of all non-melanoma skin cancers. In roughly two to five percent ...

Cancer

Scientists design protein that prods cancer-fighting T-cells

Scientists at UW Medicine's Institute for Protein Design (IPD) in Seattle have created a new protein that mimics the action of a key immune regulatory protein, interleukin 2 (IL-2).  IL-2 is a potent anticancer drug and ...

Cancer

Cancer mortality milestone: 25 years of continuous decline

A steady, 25-year decline has resulted in a 27% drop in the overall cancer death rate in the United States, translating to approximately 2.6 million fewer cancer deaths between 1991 and 2016. The data come from Cancer Statistics, ...

Cancer

Scientists advise caution in immunotherapy research

In a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caution should be exercised as we continue to better understand the biology ...

Cancer

DNA damage leads to genetic diseases and cancer

Scientists have reported that many inheritance mutations are caused by DNA damage rather than errors in DNA doubling. The study was conducted by an international research group and published in Nature Genetics.

Cancer

Mutations boost immunity: Toward a cancer vaccine

Despite significant advances in cancer research, the disease continues to exact a devastating toll. Because cancer is a disease of the body's own cells, which mutate and develop under evolutionary pressure, conventional treatments ...

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