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Gastroenterology news

Protein discovery reveals potential treatment target for common fatty liver disease

The mechanisms that cause the world's most common chronic liver disease—metabolic dysfunction-associated steatotic liver disease (MASLD)—to develop and progress are still not fully understood.

Gut microbiome could help identify people at risk of dementia

In what is thought to be the first study of its kind, researchers from Cardiff University and Imperial College London examined both gut bacteria and chemicals. Their findings could support earlier diagnosis and help spot ...

Imaging-based modalities compared for identifying at-risk MASH

FibroScan-aspartate aminotransferase (FAST) demonstrated the highest sensitivity for ruling out at-risk metabolic dysfunction-associated steatohepatitis (MASH), according to a study published in the October issue of the American ...

Kombucha may support mood and gut health

Researchers from the University of Minnesota found that drinking kombucha was associated with reduced anxiety and depressive-like behaviors in mice.

Untangling the link between depression and gut disease

Depression and gastrointestinal disorders frequently occur together. UC Irvine experts wondered if knowing which tends to be diagnosed first could shed light on the well-established but not yet fully understood gut-brain ...

How a diet free from animal proteins challenges the liver

Although a plant-based diet is recommended, notably for its environmental benefits, the health consequences of such a diet—in which protein intake is exclusively plant-based—are not yet fully understood. Scientists at the ...

Aspirin rarely used for colorectal cancer prevention

People with Lynch syndrome have a significantly increased risk of developing colorectal cancer and other types of cancer due to a hereditary predisposition. The CAPP2 study had already shown in this high-risk group that acetylsalicylic ...

Cyclosporiasis: What to know and how to prevent it

Cyclosporiasis, a parasitic infection causing "explosive diarrhea," is making headlines across the country. Dr. Stacey Rose, associate professor of internal medicine and infectious diseases at Baylor College of Medicine, ...

Microbiota dysbiosis triggers intestinal cancer stemness

Scientists at National Taiwan University College of Medicine have discovered that cancer formation is not simply caused by gene mutations. Colorectal cancers primarily originate from epithelial cells that form adenocarcinomas ...

Sweeteners slow growth of important gut bacteria in lab tests

Cambridge researchers have shown how commonly used sweeteners slow the growth of certain gut bacteria. One sweetener in particular—isosteviol—when combined with the antidepressant duloxetine, significantly impaired two important ...

Roasted and browned: How gut bacteria break down heated foods

Crusty bread, fried meat and roasted coffee owe their characteristic taste and browning to chemical reactions that occur when foods are heated. In the so-called Maillard reaction, amino acids—the building blocks of proteins—react ...

Virtual tumor predicts response to liver cancer immunotherapy

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to predict which patients with a primary liver cancer called hepatocellular ...

KRAS-targeting drugs show promise for rare appendix cancer

Targeting mutant KRAS may offer a promising new treatment option for appendix cancer, according to research from The University of Texas MD Anderson Cancer Center published in the Journal of Hematology & Oncology.

Q&A: Rise in cyclosporiasis cases

Cyclosporiasis is a gastrointestinal illness caused by the microscopic parasite Cyclospora. People contract cyclosporiasis by consuming food or water contaminated with feces containing Cyclospora parasites. Health officials ...