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Gastroenterology news

Diseases, Conditions, Syndromes

Creating a more accurate model of inflammatory bowel disease

A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

How alcohol-associated liver disease differs among races

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren't equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

Neuroscience

Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior ...

Oncology & Cancer

How AI can help researchers make esophageal cancer less deadly

Approximately 600 times a day, the esophagus ferries whatever is in your mouth down to your stomach. It's usually a one-way route, but sometimes acid escapes the stomach and travels back up. That can damage the cells lining ...

Health

Video: What is the microbiome?

Valhalla Fellow Lindsey Backman explains what the microbiome is and the roles that different members of our microbiomes play in health and disease.

Genetics

Study zeroes in on genes involved in Crohn's disease

An international consortium of researchers has identified genetic variants in 10 genes that elevate a person's susceptibility to Crohn's disease, a form of inflammatory bowel disease.

Health

Profiling pancreatitis

Simply put, pancreatitis is inflammation of the pancreas. Located behind the stomach in the upper abdomen, your pancreas produces digestive enzymes and hormones that regulate how your body produces sugar.

Immunology

Keeping balance inside and outside the small intestine

In the normal small intestine, the levels of SFB and Th17 cells are both maintained as they counterbalance each other. Th17 cells release IL-17 to limit unwanted expansion of SFB, whereas a decrease in the number of SFB eases ...

Gastroenterology

Optimization of human small intestinal organoids

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids—miniature versions of the small intestine. This will help them to better study the functioning of the small ...

Diseases, Conditions, Syndromes

Global trends in rates of IBD hospitalization examined

For countries with compounding prevalence of inflammatory bowel disease (IBD; stage 3), hospitalization rates are stable, while they are increasing for countries with accelerating incidence, according to a systematic review ...

Inflammatory disorders

New method detects gut microbes that activate immune cells

Cedars-Sinai investigators have developed a method to help identify which human gut microbes are most likely to contribute to a slew of inflammatory diseases like obesity, liver disease, inflammatory bowel disease, cancer ...

Immunology

Immune cells in the intestine have a sweet tooth

A new study led by Marc Veldhoen, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Associate Professor at Faculdade de Medicina de Lisboa (FMUL) and published today in the scientific ...

Radiology & Imaging

Diagnostic accuracy of MRE indices studied for active crohn disease

Magnetic resonance enterography (MRE) indices have high diagnostic sensitivity, but low specificity, for active terminal ileal (TI) Crohn disease (CD), according to a study recently published in the Journal of Crohn's & Colitis.