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Gastroenterology news

Inflammatory disorders

Study highlights pervasiveness of inflammation in American diet

Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.

Pediatrics

Button cells: Serious health damage possible for small children if swallowed

If button cells are swallowed, they may get stuck in the esophagus. This can sometimes lead to severe damage to the mucous membranes. "Over the past 10 years, clinics and poison centers have reported several hundred cases ...

Diseases, Conditions, Syndromes

Creating a more accurate model of inflammatory bowel disease

A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

How alcohol-associated liver disease differs among races

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren't equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

Neuroscience

Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior ...

Oncology & Cancer

How AI can help researchers make esophageal cancer less deadly

Approximately 600 times a day, the esophagus ferries whatever is in your mouth down to your stomach. It's usually a one-way route, but sometimes acid escapes the stomach and travels back up. That can damage the cells lining ...

Gastroenterology

Factors associated with nonresponse to FMT identified in IBS

For patients with irritable bowel syndrome (IBS), those who are male and/or have low Alistipes levels are more likely to be nonresponders to fecal microbiota transplantation (FMT), according to a study published online March ...

Immunology

Immune responses in chronic inflammatory bowel diseases

Chronic inflammatory bowel diseases (IBDs) like Crohn's disease and ulcerative colitis are characterized by inflammation of the gastrointestinal tract which flares up in phases and which is accompanied by abdominal pain, ...

Immunology

Deciphering gut microbiome 'chatter' to combat IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms. Crohn's Disease and Ulcerative ...

Medications

Green synthesis of drug candidate for inflammatory bowel disease

Inflammatory bowel disease (IBD), characterized by a chronic inflammation of the digestive tract, is currently treated with steroids and antibody drugs. However, steroids have side effects, such as delayed healing, and antibody ...

Oncology & Cancer

Pediatric-onset inflammatory bowel disease may up cancer risk

Patients with pediatric-onset inflammatory bowel disease (IBD) may have an increased risk for developing cancer, particularly gastrointestinal cancers, according to a meta-analysis published online March 1 in JAMA Network ...

Parkinson's & Movement disorders

The gut-brain axis in Parkinson's disease

Parkinson's disease (PD) is a progressive and complex disorder that affects multiple parts of the brain but also other organ systems. Symptoms start gradually, sometimes with a barely noticeable tremor in just one hand. Tremor ...

Oncology & Cancer

6 healthy steps to preventing colon cancer

Colon cancer can be a devastating diagnosis, but there are a number of steps you can take to reduce your risk of tumors, an expert says.

Oncology & Cancer

Nitrate levels in drinking water may be related to bowel cancer

The formation of cancer-causing chemicals in the gut could be at the heart of understanding how high levels of nitrate in our drinking water contribute to increasing the risk of bowel (colorectal) cancer, New Zealand researchers ...

Alzheimer's disease & dementia

Study: Gut health plays a role in Alzheimer's development

A series of experiments presented today at the Alzheimer's Research UK 2022 Conference at the Brighton Centre, has implicated the health of the gut in the development of Alzheimer's disease.

Gastroenterology

Intestinal cells change functions during their lives

Intestinal cells can change specializations during their lives. The BMP signaling pathway—an important communication mechanism between cells—appears to be the driver of these changes. That is what scientists from the ...

Immunology

Discovery of an innate immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection model, scientists from ...