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Gastroenterology news

Diseases, Conditions, Syndromes

How doxycycline for STI prevention affects the gut microbiome

Taking a dose of the oral antibiotic doxycycline after a high-risk sexual encounter has dramatically reduced the incidence of sexually transmitted infections (STIs) in places where the strategy is being tried.

Medical research

Tuft cells act as regenerative stem cells in the human intestine, study finds

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation damage, and contribute ...

Inflammatory disorders

Study highlights pervasiveness of inflammation in American diet

Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.

Diseases, Conditions, Syndromes

Creating a more accurate model of inflammatory bowel disease

A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

How alcohol-associated liver disease differs among races

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren't equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

Neuroscience

Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior ...

Gastroenterology

Probiotics not recommended for most digestive conditions

(HealthDay)—Probiotics are not recommended for most digestive conditions, according to a clinical practice guideline issued by the American Gastroenterological Association and published online June 9 in Gastroenterology.

Diseases, Conditions, Syndromes

Insight on novel genetic approaches to metabolic liver diseases

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications. NAFLD affects over 30% of Americans, and is characterized as a fatty liver, which can progress ...

Neuroscience

Bacteria in the gut have a direct line to the brain

With its 100 million neurons, the gut has earned a reputation as the body's "second brain"—corresponding with the real brain to manage things like intestinal muscle activity and enzyme secretions. A growing community of ...

Gastroenterology

Arthritis drug could let coeliac patients eat gluten

Tofacitinib, a Janus kinase inhibitor approved to treat rheumatoid arthritis and bowel diseases, may allow patients with celiac disease to eat gluten without experiencing intestinal and extraintestinal symptoms. A case report ...

Surgery

Updated guidelines on surgery for Crohn's disease

Although rates of surgery for Crohn's disease have decreased over the years, many patients still require surgical treatment - due to inadequate responses to medical therapy, severe attacks of acute colitis, and many other ...

Gastroenterology

How to repair your gut

In a world first, Monash University researchers have identified a key biomolecule that enhances the repair of your gut lining by prompting stem cells to regenerate damaged tissue.

Gastroenterology

High-fat diet with antibiotic use linked to gut inflammation

Irritable bowel syndrome (IBS) affects approximately 11% of people worldwide. It is characterized by recurring episodes of abdominal pain, bloating and changes in bowel habits. IBS patients with mucosal inflammation and changes ...

Diseases, Conditions, Syndromes

Multidisciplinary approach more effective for gut disorders

Patients with gastrointestinal disorders such as irritable bowel syndrome (IBS) and constipation have greater symptom relief and improved wellbeing when treated at multidisciplinary clinics, new research shows.

Diseases, Conditions, Syndromes

Risk for COVID-19 increased for adults taking PPIs

(HealthDay)—Adults taking proton pump inhibitors (PPIs) have an increased risk for having a positive COVID-19 test, with evidence of a dose-response relationship, according to a study published online July 7 in preprint ...

Gastroenterology

Gut microbiota provide clues for treating diabetes

The individual mix of microorganisms in the human gastrointestinal tract provides vital clues as to how any future incidence of type 2 diabetes can be predicted, prevented and treated. This is demonstrated in a population ...

Inflammatory disorders

Better treatment for people with inflammatory bowel disease

Finding the right treatment for people living with chronic intestinal inflammation, also known as inflammatory bowel disease (IBD), might soon be getting easier. World IBD Day happens on 19 May each year, with the goal to ...

Gastroenterology

Fighting E. coli with E. coli

According to findings published this week in mBio, Nissle, a strain of Escherichia coli, is harmless to intestinal tissue and may protect the gut from enterohemorrhagic E. coli, a pathogen that produces Shiga toxin.