Last update:
Genetics news
Genetics
Genetic mechanisms may reveal retinal vascular disease therapeutic targets
Investigators led by Tsutomu Kume, Ph.D., professor of Medicine in the Division of Cardiology and of Pharmacology, have identified novel genetic mechanisms that regulate blood vessel growth in the retina and may also serve ...
38 minutes ago
0
0
Genetics
Researchers develop new tool to aid processing of spatial transcriptomic data
Researchers from Children's Hospital of Philadelphia (CHOP) have developed a new tool to help analyze data collected from spatial transcriptomics technologies (SRTs), which simultaneously profile gene expression and spatial ...
1 hour ago
0
0
New AI tool finds rare variants linked to heart disease in 17 genes
Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease ...
5 hours ago
0
2
Researchers discover a protein that prunes nerve endings, regulating sensitivity to pain
Like treetops reaching high into the sky to sense the sunlight, our sensory neurons—whose role is to collect information about what is happening in and around the body—grow long, intricate extensions known as axons. These ...
22 hours ago
0
25
Scientists discover a gene for trust—here's how it could be linked to good health
If a distressed stranger knocked on your door asking to use your phone, would you oblige? How about lending them a fiver for the bus, if they assured you they'd return and pay you back? In today's fractured world, trust seems ...
23 hours ago
0
25
Discovery unveils key to heart development in womb, unravels cause of spongy heart disease
Having explored how the heart is formed in utero, a University of Houston pharmacology researcher is reporting how cells and molecules act during that early formation and what might cause the heart disease called left ventricular ...
21 hours ago
0
7
'Whole family cried': New gene therapy offers hope for deaf kids
Zhu Yangyang babbles away like a typical happy three-year-old, calling out for "mama" and "papa" and accurately naming colors—a remarkable achievement considering he was completely deaf just months ago.
Jun 8, 2024
0
0
Scientists develop new CRISPR gene editing platform for precision medicine and cancer treatment
Researchers at Columbia University College of Dental Medicine have developed an exosome-based platform, "safeEXO-Cas," that significantly enhances the delivery of CRISPR/Cas9 genome editing components to specific cells and ...
Jun 7, 2024
0
160
New study sheds light on the rate, nature and transmission of mitochondrial DNA mutations in humans
A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its maternal transmission.
Jun 7, 2024
0
53
When is genome sequencing advisable? Human geneticists conduct clinical reference study
Scientists from the Broad Institute of MIT and Harvard, Harvard Medical School, and the University of Leipzig Medical Center have shown in two independent patient cohorts when a genome sequencing is beneficial in the diagnosis ...
Jun 7, 2024
0
39
Women have a higher genetic risk for PTSD, study finds
Women are twice as likely as men to develop post-traumatic stress disorder, but the factors contributing to this disparity have largely remained unsettled. A research team led by Virginia Commonwealth University and Lund ...
Jun 7, 2024
0
1
Study uncovers how cancer stem cells spread and resist treatment
NDORMS researchers have identified a critical axis that controls the formation and behavior of cancer stem cells (CSCs), a subpopulation of cells that influence how lethal the cancer can be, its resistance to chemotherapy, ...
Jun 6, 2024
0
18
Researchers detail molecular pathway that impacts pancreatic cancer progression and treatment response
Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or "oncogene," and how its activities ...
Jun 6, 2024
0
0
Long-read RNA sequencing reveals key gene expressions in Alzheimer's disease
Researchers at the University of Kentucky Sanders-Brown Center on Aging are working to develop a pre-symptomatic disease diagnostic tool for Alzheimer's disease.
Jun 6, 2024
0
43
Study suggests father's diet before conception influences children's health
Dr. Raffaele Teperino, head of the "Environmental Epigenetics" research group at Helmholtz Munich, along with his research team, has examined the impact of paternal diet on children's health—specifically, the influence ...
Jun 5, 2024
0
49
Genetics study points to potential treatments for restless leg syndrome
Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults. The discovery could help identify those individuals at greatest risk of the condition and point to potential ...
Jun 5, 2024
2
74
New insights on cellular clones and inflammation in bones
As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...
Jun 5, 2024
0
41
Prostate cancer study reveals molecular switch linked to lineage plasticity, therapy resistance
Two genes working in tandem play a critical role in shaping the identity and behavior of prostate cancer cells and their response to treatment, UT Southwestern Medical Center researchers report.
Jun 5, 2024
0
0
Study finds maternal obesity in mice increases microRNA levels in the hypothalamus in offspring, leading to overeating
Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a study publishing June 4 in the open-access journal PLOS Biology by Laura Dearden and Susan ...
Jun 4, 2024
0
8
Rare disease's mutation could explain more common conditions
TREX1 is a gene that is supposed to direct the maintenance of the entire body's DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a ...
Jun 4, 2024
0
18
