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Genetics news

Genetics

DNA repair gene linked to male infertility

A key DNA repair gene known as X-ray repair cross-complementing group 1, or XRCC1, plays a vital role in maintaining genomic stability and is highly expressed in the early stages of sperm cell development (also known as spermatogenesis). ...

Genetics

Estimating the efficacy and cost of curative gene therapy for beta-thalassemia

Gene therapy offers the promise of a cure for beta-thalassemia and a new study has shown that it is associated with fewer complications and hospital admissions over 2 years than treatment by allogeneic hematopoietic stem ...

Genetics

Rare genetic change provides clues to pancreas development

Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas. The study from the Wellcome Sanger Institute, the University of Exeter and collaborators ...

Cancer

Scientists alter 3-D genome using 'small molecules'

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs. This work opens up the prospect of developing a new ...

Genetics

SRC-1 gene variants linked to human obesity

Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side. Contributing toward this goal, a team led by researchers at ...